P
Paul H. M. Savelkoul
Researcher at Maastricht University
Publications - 253
Citations - 12176
Paul H. M. Savelkoul is an academic researcher from Maastricht University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 52, co-authored 233 publications receiving 10186 citations. Previous affiliations of Paul H. M. Savelkoul include Vanderbilt University Medical Center & University of Amsterdam.
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Journal ArticleDOI
Presence of mcr-1-positive Enterobacteriaceae in retail chicken meat but not in humans in the Netherlands since 2009
Marjolein Kluytmans– van den Bergh,Pepijn Huizinga,Marc J. M. Bonten,Martine P. Bos,Katrien De Bruyne,Alexander W. Friedrich,John W. A. Rossen,Paul H. M. Savelkoul,Paul H. M. Savelkoul,Jan Kluytmans +9 more
TL;DR: It is indicated that mcr-1-based colistin-resistance currently poses no threat to healthcare in the Netherlands, but continued monitoring of colistIn resistance and its underlying mechanisms in humans, livestock and food is needed.
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Bile acids drive the newborn's gut microbiota maturation.
N. van Best,N. van Best,Ulrike Rolle-Kampczyk,Frank G. Schaap,Frank G. Schaap,Marijana Basic,S. W. M. Olde Damink,S. W. M. Olde Damink,André Bleich,Paul H. M. Savelkoul,M. von Bergen,M. von Bergen,John Penders,Mathias W. Hornef +13 more
TL;DR: The authors investigate the impact of the developing host hepatic metabolism on the murine intestinal microbiota composition with comparative analysis at immediate postnatal period, early infancy and weaning and adulthood.
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Nosocomial outbreak of multi-resistant Acinetobacter baumannii on a surgical ward : epidemiology and risk factors for acquisition
J.G.M. Koeleman,G.A. Parlevliet,L. Dijkshoorn,Paul H. M. Savelkoul,Christina M. J. E. Vandenbroucke-Grauls +4 more
TL;DR: Patients admitted on a general surgical ward colonized or infected with multi-resistant A. baumannii strains should alert the hospital infection control team, and prompt implementation of strict infection prevention measures to prevent further spread is advised.
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Faster Identification of Pathogens in Positive Blood Cultures by Fluorescence In Situ Hybridization in Routine Practice
Remco P. H. Peters,Paul H. M. Savelkoul,Alberdina M. Simoons-Smit,S. A. Danner,Christina M. J. E. Vandenbroucke-Grauls,Christina M. J. E. Vandenbroucke-Grauls,Michiel A. van Agtmael +6 more
TL;DR: In this paper, the authors evaluated the performance, time to identification, and potential clinical benefits of FISH compared to those of conventional culture methods in routine practice, and concluded that FISH allows rapid and reliable identification of the majority of microorganisms in growth-positive blood cultures.
Journal ArticleDOI
Improved detection of microbial DNA after bead-beating before DNA isolation.
Richard F. de Boer,Remco P. H. Peters,Sonja Gierveld,T. Schuurman,Mirjam Kooistra-Smid,Paul H. M. Savelkoul +5 more
TL;DR: Physical disruption by bead-beating with 0.1mm beads in combination with MagNA Pure DNA III extraction enhances microbial lysis of diverse Gram-positive microorganisms and may be used to optimize DNA extraction protocols in routine clinical diagnostics.