P
Paul H. M. Savelkoul
Researcher at Maastricht University
Publications - 253
Citations - 12176
Paul H. M. Savelkoul is an academic researcher from Maastricht University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 52, co-authored 233 publications receiving 10186 citations. Previous affiliations of Paul H. M. Savelkoul include Vanderbilt University Medical Center & University of Amsterdam.
Papers
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Journal ArticleDOI
Rectal swabs for analysis of the intestinal microbiota.
Andries E. Budding,Matthijs E. Grasman,Anat Eck,Johannes A. Bogaards,Christina M. J. E. Vandenbroucke-Grauls,Adriaan A. van Bodegraven,Paul H. M. Savelkoul +6 more
TL;DR: It is found that rectal swabs appeared to be a convenient means of sampling the human gut microbiota, and may be ideally suited for clinical diagnostics and large-scale studies.
Journal ArticleDOI
The vaginal microbiome as a predictor for outcome of in vitro fertilization with or without intracytoplasmic sperm injection: a prospective study
R. Koedooder,M. Singer,Sam Schoenmakers,Paul H. M. Savelkoul,Paul H. M. Savelkoul,Servaas A. Morré,Servaas A. Morré,J. D. de Jonge,L. Poort,W. J.S.S. Cuypers,Nicole G. M. Beckers,Frank J. M. Broekmans,Ben J. Cohlen,J. E. den Hartog,Kathrin Fleischer,Cornelis B. Lambalk,Jesper M. J. Smeenk,Andries E. Budding,Joop S.E. Laven +18 more
TL;DR: Results indicate that vaginal microbiome profiling with the use of interspace profiling (IS-pro) technique enables stratification of the chance of becoming pregnant prior to the start of an IVF or IVF-ICSI treatment.
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Fecal microbial composition of ulcerative colitis and Crohn's disease patients in remission and subsequent exacerbation.
Edgar S. Wills,Daisy Jonkers,Paul H. M. Savelkoul,Ad A.M. Masclee,Marieke Pierik,John Penders +5 more
TL;DR: Shifts in microbial composition in IBD patients with changing disease activity over time seem to be patient-specific, and are more pronounced in CD than in UC patients.
Journal ArticleDOI
Widespread Transfer of Resistance Genes between Bacterial Species in an Intensive Care Unit: Implications for Hospital Epidemiology
Nashwan al Naiemi,Birgitta Duim,Paul H. M. Savelkoul,Lodewijk Spanjaard,Evert de Jonge,Aldert Bart,Christina M. J. E. Vandenbroucke-Grauls,Menno D. de Jong +7 more
TL;DR: A transferable plasmid encoding SHV-12 extended-spectrum β-lactamase, TEM-116, and aminoglycoside resistance was responsible for two sequential clonal outbreaks of Enterobacter cloacae and Acinetobacter baumannii bacteria.
Journal ArticleDOI
Optimization of Real-Time PCR Assay for Rapid and Sensitive Detection of Eubacterial 16S Ribosomal DNA in Platelet Concentrates
Tamimount Mohammadi,Henk W. Reesink,Christina M. J. E. Vandenbroucke-Grauls,Paul H. M. Savelkoul +3 more
TL;DR: A real-time PCR assay was developed for rapid detection of eubacterial 16S ribosomal DNA in platelet concentrates as discussed by the authors, but the sensitivity of this assay can be hampered by contaminating DNA in the PCR reagents.