P
Paul M. Matthews
Researcher at Imperial College London
Publications - 641
Citations - 102773
Paul M. Matthews is an academic researcher from Imperial College London. The author has contributed to research in topics: Multiple sclerosis & White matter. The author has an hindex of 140, co-authored 617 publications receiving 88802 citations. Previous affiliations of Paul M. Matthews include John Radcliffe Hospital & King's College London.
Papers
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Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases
Erik Nutma,Nurun Nahar Fancy,Maria Weinert,Manuel C. Marzin,Stergios Tsartsalis,Robert C. Muirhead,Irene Falk,Joy de Bruin,David Hollaus,Robin Pieterman,Jasper J. Anink,David Story,Siddharthan Chandran,Jiabin Tang,Maria Chiara Trolese,Takashi Saito,Takaomi C. Saido,Katie Wiltshire,Paula Beltran-Lobo,Alexandra Philips,Jack P. Antel,Luke M. Healy,Craig S. Moore,Caterina Bendotti,Eleonora Aronica,Carola I. Radulescu,Samuel J. Barnes,David W. Hampton,P. Ven Der Valk,Steven Jacobson,Paul M. Matthews,Sandra Amor,David R. Owen +32 more
TL;DR: It is shown that TSPO expression in human myeloid cells is related to different phenomena than in mice, and that T SPO PET reflects density of inflammatory cells rather than activation state, and is mechanistically linked to classical pro-inflammatory myeloids cell function in rodents but not humans.
Journal ArticleDOI
Decade in review-multiple sclerosis: new drugs and personalized medicine for multiple sclerosis.
TL;DR: The past decade of multiple sclerosis research has been marked by important advances in understanding the disease, a dramatic increase in the range of treatment options and a new spirit of data sharing in research for patient benefit.
Journal ArticleDOI
Tensor Dropout for Robust Learning
Arinbjörn Kolbeinsson,Jean Kossaifi,Yannis Panagakis,Adrian Bulat,Animashree Anandkumar,Ioanna Tzoulaki,Paul M. Matthews +6 more
TL;DR: This article proposed tensor dropout, a randomization technique that can be applied to tensor factorizations, such as those parametrizing tensor layers, to improve robustness to adversarial attacks.
Journal ArticleDOI
Effect of short-term escitalopram treatment on neural activation during emotional processing
Eduard Maron,Matthew B. Wall,Ray Norbury,Beata R. Godlewska,Sylvia Terbeck,Philip J. Cowen,Paul M. Matthews,David J. Nutt +7 more
TL;DR: It is shown that escitalopram exerts its rapid direct effect on emotional processing via attenuation of neural activation in pathways involving medial frontal gyrus and amygdala, an effect that seems to be distinguishable from that of other SSRIs.
Book
Underhill and Hayton Law Relating to Trusts and Trustees.
TL;DR: "DIVISION ONE - PRELIMINARY DEFINITIONS DIVISION TWO - EXPRESS or DECLARED TRUSTS 1. Matters essential to the prima facie validity of an express trust 2. Validity of declared trusts in relation to latent matters 4.