Per A. Peterson

TL;DR: It is demonstrated that several proteasomal sub units, including MHC-encoded subunits, are regulated by interferon gamma, which strongly suggest that the immune system has recruited proteasomes for antigen processing.

TL;DR: Analysis of antigen presentation by B cells from mice lacking H2-O, together with biochemical analysis using purified HLA-DO and Hla-DM molecules, suggests that HLA’s role in peptide loading may be affected, which may serve to decrease the presentation of antigens internalized by fluid-phase endocytosis, thus concentrating the B cell-mediated antigen presentation to antigeninternalized by membrane immunoglobulin.

TL;DR: The complete amino acid sequence of the cell attachment domain of human plasma fibronectin has been determined by automated sequential degradation of a peptic fragment comprising this region and of peptides derived from this fragment by digestion with thermolysin, staphylococcal V8 protease, cyanogen bromide cleavage, and partial acid hydrolysis.

TL;DR: It is demonstrated that IRAK plays an important role in IL-18–induced signaling and function and production by activated NK cells in an acute murine cytomegalovirus infection was significantly reduced despite normal induction of NK cytotoxicity.

TL;DR: Differential gene expression occurs in the process of development, maintenance, injury, and death of unicellular as well as complex organisms as mentioned in this paper and is usually identified by comparing steady-state mRNA concentrations.