Per A. Peterson

TL;DR: Weak electrostatic complementarity between Asp77 on the alpha1 helix of Kb and 2C is enhanced in the allogeneic complex by closer proximity of QL9 peptide residue AspP8 to the 2C HV4 loop.

TL;DR: A soluble form of a mouse class I major histocompatibility antigen (H-2Kb) expressed in transfected Drosophila melanogaster cells is expressed andKinetic analyses showed that the peptide binding is rapid and reversible and dependent on the heavy chains being assembled with beta 2m, and no dominant residue was observed at the carboxyl terminus of bound peptides.

TL;DR: Transfected Drosophila melanogaster cells can express large quantities of class I major histocompatibility complex molecules, and all beta 2-microglobulin-induced conformers of empty heavy chains seem to be unified in a common rigid conformation on peptide binding.

TL;DR: A clone containing the entire I-A β gene and a separate exon encoding a β-chain second domain (A β2) was isolated from a mouse spleen DNA cosmid library of the b haplotype.

TL;DR: The subunits of immunoglobulins, class I antigens and class II antigen are related evolutionarily, and the complete amino acid sequence is predicted.