P
Peter C. Taylor
Researcher at University of Oxford
Publications - 397
Citations - 19020
Peter C. Taylor is an academic researcher from University of Oxford. The author has contributed to research in topics: Rheumatoid arthritis & Arthritis. The author has an hindex of 63, co-authored 359 publications receiving 16347 citations. Previous affiliations of Peter C. Taylor include HealthPartners & University of Cambridge.
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Proceedings ArticleDOI
OP0040 Synovial cell infiltration in acpa-ve patients displays similar signatures to other seronegative inflammatory arthritis. results from the pathobiology of early arthritis cohort (PEAC)
Gloria Lliso-Ribera,Frances Humby,Alessandra Nerviani,Marie-Astrid Boutet,Stephen Kelly,Michele Bombardieri,Myles Lewis,Rebecca Hands,V. Rocher,F Bene,Christopher D. Buckley,Peter C. Taylor,Iain B. McInnes,C. Pitzalis +13 more
TL;DR: This study examines in a cohort of therapy naïve, early inflammatory arthritis patients whether ACPA-ve RA can be defined at disease initiation according to synovial pathobiological signatures and suggests shared pathophysiological mechanisms between PsA and ACPA -ve RA and support a role for future refinement of diagnosis.
Journal ArticleDOI
The future of TNF-α antagonism
TL;DR: Although the cause of rheumatoid arthritis (RA) remains unknown, advances in molecular technology have facilitated identification of novel therapeutic targets including cell subsets, cytokines and other molecules contributing to the inflammatory and destructive aspects of this syndrome.
Journal ArticleDOI
Characterization of disease course and remission in early seropositive rheumatoid arthritis: results from the TACERA longitudinal cohort study
Michael R. Barnes,Sarah Brockbank,Ian N. Bruce,Coziana Ciurtin,Andrew P. Cop,Michael R. Ehrenstein,Paul Emery,Benjamin A Fisher,John D. Isaacs,Ruth Matthews,Iain B. McInnes,Hayley Noble,Ayako Wakatsuki Pedersen,Costantino Pitzalis,Karim Raza,Anthony Rowe,Gemma Simpson,Dominic Stringer,Peter C. Taylor,Brian D. M. Tom,Yujie Zhong +20 more
TL;DR: In this article, a longitudinal observational study of newly diagnosed, initially treatment-naive patients with seropositive rheumatoid arthritis (RA) was carried out in 28 UK centres, where multiple clinical and laboratory measures were collected every 3 months for up to 18 months.
Journal ArticleDOI
Novel methodology to discern predictors of remission and patterns of disease activity over time using rheumatoid arthritis clinical trials data
Bdm Tom,Deborah P M Symmons,Sarah Brockbank,Claudio Carini,Andrew P. Cope,Ehrenstein,Benjamin A Fisher,Carl S. Goodyear,Neil Gozzard,Ray Harris,K Hicks,Sally Hollis,A Hughes-Morley,John D. Isaacs,B Kola,Iain B. McInnes,Christopher M Mela,Gerry Parker,Ayako Wakatsuki Pedersen,Frederique Ponchel,T Sabin,David Scott,Ian C. Scott,MA Sleeman,Peter C. Taylor,Wayne Tsuji,Y Zhong,Catharien M. U. Hilkens,Amy E. Anderson,P Stocks,Dennis Lendrem,J Tarn,George Davey Smith,B Allen,J Casement,J Diboll,R Harry,G Simpson,R Toward,H Noble,A Parke,W Wu,Fiona Clarke,James N. Galloway,Heidi Lempp,Fowzia Ibrahim,S Schwank,G Molyneux,T Lazarov,Frederic Geissmann,Iona Donnelly,A. Gilmour,AT Virlan,Duncan Porter,Paul Emery,Jehan J. El-Jawhari,Rekha Parmar,MF McDermot,Maya H Buch,Christopher D. Buckley,Stephen P. Young,P Jones,Karim Raza,A Filer,Costantino Pitzalis,Barnes,David Watson,Evan Tzanis,Georgina Thorborn,Liliane Fossati-Jimack,S Kelly,F Humby,Michele Bombardieri,Sharmila Rana,Z Jia,Katriona Goldmann,Myles Lewis,G Altobelli,Christopher R. John,S Martins,D Nguyen,H Ali,Coziana Ciurtin,J Worthington,Ian N. Bruce,Jamie C. Sergeant,Smm Verstappen,F Stirling,Farewell,Sarah Keidel,C Cuff,Marc C. Levesque,A Long,Z Liu,S Lipsky,B Harvey,M Macoritto,F Hong,S Kaymakcalan,N Ward,S Talbot,D Padhji,Matthew A. Sleeman,D Finch,A Herath,Catharina Lindholm,M Jenkins,M Ho,C Marshall,M Page,H Edwards,A Cuza,Anthony Rowe,FB Capdevila,M Loza,M Curran,Denny Verbeeck,D Baker,I Vranic,CT Mela,S Wright,L Rowell,E Vernon,N Joseph,N Payne,R Rao,Michael Binks,Alexandra Belson,Ludbrook,H Tipney,J Ellis,S Hasan,A Didierlaurent,W Burny,A Haynes,C Larminie,D Dastros-Pitel,S Jelinsky,M Hodge,M Maciejewski,D Ziemek,P Schulz-Knappe,H-D Zucht,P Budde,Mark Coles,JA Butler,Simon Read +146 more
TL;DR: Latent class mixed models supported differential non-biological therapy response, with three distinct trajectories observed in both MTX-naïve andMTX-exposed patients, with finding should be useful when designing future RA trials and interpreting results of biomarker studies.
Journal ArticleDOI
Respiratory symptoms in a patient on anti-tumour necrosis factor therapy; beware the negative enzyme linked immuno-spot (ELISpot) in suspected mycobacterial disease
TL;DR: A case is presented which illustrates that ELISpot can be negative in mycobacterial disease and the tuberculin skin test (TST) is of limited benefit in immuno-supressed individuals who often fail to mount a delayed type hypersensitivity reaction.