P
Peter R. Galle
Researcher at University of Mainz
Publications - 44
Citations - 27319
Peter R. Galle is an academic researcher from University of Mainz. The author has contributed to research in topics: Fas receptor & Apoptosis. The author has an hindex of 29, co-authored 44 publications receiving 22582 citations. Previous affiliations of Peter R. Galle include Heidelberg University & University Hospital Heidelberg.
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Journal ArticleDOI
Sorafenib in Advanced Hepatocellular Carcinoma
Josep M. Llovet,Sergio Ricci,Vincenzo Mazzaferro,Philip Hilgard,Edward Gane,Jean-Frédéric Blanc,André Cosme de Oliveira,Armando Santoro,Jean-Luc Raoul,Alejandro Forner,Myron Schwartz,Camillo Porta,Stefan Zeuzem,Luigi Bolondi,Tim F. Greten,Peter R. Galle,Jean Francois Seitz,Ivan Borbath,Dieter Häussinger,Tom Giannaris,Minghua Shan,M. Moscovici,D. Voliotis,Jordi Bruix +23 more
TL;DR: In patients with advanced hepatocellular carcinoma, median survival and the time to radiologic progression were nearly 3 months longer for patients treated with sorafenib than for those given placebo.
Journal ArticleDOI
Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma
Richard S. Finn,Shukui Qin,Masafumi Ikeda,Peter R. Galle,Michel Ducreux,Tae-You Kim,Masatoshi Kudo,Valeriy Breder,Philippe Merle,Ahmed O Kaseb,Daneng Li,Wendy Verret,Derek-Zhen Xu,Sairy Hernandez,Juan Liu,Chen Huang,Sohail M. Mulla,Yulei Wang,Ho Yeong Lim,Andrew X. Zhu,Ann-Lii Cheng,IMbrave Investigators +21 more
TL;DR: In patients with unresectable hepatocellular carcinoma, atezolIZumab combined with bevacizumab resulted in better overall and progression-free survival outcomes than sorafenib.
Journal ArticleDOI
Simplified criteria for the diagnosis of autoimmune hepatitis
E. M. Hennes,Mikio Zeniya,Albert J. Czaja,Albert Parés,George N. Dalekos,Edward L. Krawitt,Paulo Lisboa Bittencourt,Gilda Porta,Kirsten Muri Boberg,Harald Hofer,Francesco B. Bianchi,Minoru Shibata,Christoph Schramm,Barbara Eisenmann de Torres,Peter R. Galle,Ian G. McFarlane,Hans-Peter Dienes,AW Lohse +17 more
TL;DR: A reliable diagnosis of AIH can be made using a very simple diagnostic score proposed, which is the diagnosis of probable AIH at a cutoff point greater than 6 points and definite AIH 7 points or higher.
Journal ArticleDOI
Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma
John Bridgewater,Peter R. Galle,Shahid A. Khan,Josep M. Llovet,Joong-Won Park,Tushar Patel,Timothy M. Pawlik,Gregory J. Gores +7 more
TL;DR: University College, London Cancer Institute, 72 Huntley St.
Journal ArticleDOI
Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion?
Susanne Strand,Walter J. Hofmann,Hubert Hug,Martina Müller,Gerd Otto,Dennis Strand,Sara M. Mariani,Wolfgang Stremmel,Peter H. Krammer,Peter R. Galle +9 more
TL;DR: The data suggest that tumor cells can evade immune attack by down–regulation of the CD95 receptor and killing of lymphocytes through expression of CD95L, which is an important mediator of T–cell cytotoxicity.