Peter W. Andrews

TL;DR: Since SSEA-1 has been suggested to play a role in some morphogenetic cell-cell interactions during embryonic development, the induction of this antigen at inappropriate times might provide one mechanism whereby intrauterine infection with HCMV can damage the developing fetal nervous system.

TL;DR: Reverse transcription-PCR and Northern and Western blot analyses indicate that mRNA and protein encoded by the Brachyury gene are expressed by the pluripotent human embryonal carcinoma cell line NTERA2 and are only modestly down-regulated during retinoic acid-induced differentiation.

TL;DR: Data suggest that the apoptotic response was properly restored during reprogramming with mRNA, and that apoptosis is an important mechanism shared by hiPS and hES cells to maintain their genomic integrity when a replication stress occurs.

TL;DR: Results indicate that the normally low threshold of apoptosis in hPSCs can safeguard their genome integrity by clearing cells undergoing abnormal division, reducing the sensitivity of h PSCs to damage caused by erroneous mitosis and increases the risk of gaining aneuploidy.

TL;DR: In this paper, the Miocene sedimentary strata at Pasalar are described in relation to their probable source, and they are divided into upper and lower series, including five sedimentary units which are all highly calcareous, the unfossiliferous lower calcayous silt at the base of the sequence; the greenish grey sand, a poorly sorted massive deposit of sands and gravels accumulated over a short period of time and richly fossiliferous; the upper sand, similarly to the lower but with some fossils.