P
Peter W. Andrews
Researcher at University of Sheffield
Publications - 286
Citations - 22367
Peter W. Andrews is an academic researcher from University of Sheffield. The author has contributed to research in topics: Embryonic stem cell & Cellular differentiation. The author has an hindex of 71, co-authored 280 publications receiving 21323 citations. Previous affiliations of Peter W. Andrews include East Sussex County Council & Wistar Institute.
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Book ChapterDOI
Human—Mouse Teratocarcinoma Hybrids
TL;DR: Experimental approaches to understanding early human development are urgently required following the increased use of in vitro fertilization and cultivation of embryos for treatment of infertility and the largely unknown origins of many human birth defects.
Journal ArticleDOI
Nuclear proteome dynamics in differentiating embryonic carcinoma (NTERA-2) cells.
E. Pewsey,C. Bruce,Peter D. Tonge,Caroline A. Evans,Saw Yen Ow,A. S. Georgiou,Phillip C. Wright,Peter W. Andrews,Alireza Fazeli +8 more
TL;DR: This study aimed to characterize the nuclear protein dynamics of NTERA-2 cells undergoing retinoic acid-induced differentiation, specifically on the first six days of differentiation, to provide insight into the earliest differentiation events, and employed techniques to specifically monitor the nuclear proteome.
Journal Article
Embryonal carcinoma cells differentiate into parietal endoderm via an intermediate stage corresponding to primitive endoderm.
TL;DR: It is suggested that differentiation of F9 EC cells into parietal yolk sac-like cells can occur along two distinct pathways: 1) direct under the combined influence of RA and cAMP; and 2) indirect, under the influence ofRA alone, in which cells first differentiate into primitive endoderm.
Journal ArticleDOI
Definition of three species-specific monoclonal antibodies recognizing antigenic structures present on human embryonal carcinoma cells which undergo modulation during in vitro differentiation.
C. Blaineau,Francine Connan,Danielle Arnaud,Peter W. Andrews,L. K. Williams,J. McIlhinney,Philip Avner,Philip Avner +7 more
TL;DR: Results taken together with the extremely limited in vivo tissue distribution of the defined antigens suggest that the 5.I.