P
Peter W. Andrews
Researcher at University of Sheffield
Publications - 286
Citations - 22367
Peter W. Andrews is an academic researcher from University of Sheffield. The author has contributed to research in topics: Embryonic stem cell & Cellular differentiation. The author has an hindex of 71, co-authored 280 publications receiving 21323 citations. Previous affiliations of Peter W. Andrews include East Sussex County Council & Wistar Institute.
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mGluR5 is involved in dendrite differentiation and excitatory synaptic transmission in NTERA2 human embryonic carcinoma cell-derived neurons.
Hyeonseon Park,Aniko Varadi,Heon Seok,Heon Seok,Jihoon Jo,Jihoon Jo,Heather Gilpin,Chee Gee Liew,Sungjun Jung,Peter W. Andrews,Elek Molnár,Kwangwook Cho +11 more
TL;DR: It is shown that NTERA2-derived neurons express functional mGluR5, which is involved in Ca2+ signalling, and this activity at early stages of differentiation is likely to play a role in the development of multipotent cell- derived neurons.
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Covalent binding of lactosaminoglycans and heparan sulphate to fibronectin synthesized by a human teratocarcinoma cell line.
TL;DR: FibronECTin synthesized by the human teratocarcinoma cell line 2102Ep carries covalently bound lactosaminoglycan and heparan sulphate, whereas human fibroblast fibronectin does not.
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Toward safer regenerative medicine
TL;DR: A newly identified surface marker on human embryonic stem cells allows rare tumor-forming cells to be removed from preparations of differentiated cells.
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Human embryonic stem cells: 10 years on.
Paul J. Gokhale,Peter W. Andrews +1 more
TL;DR: The recent appearance of technology to convert somatic cells to ‘induced Pluripotent Stem Cells’ closely resembling ES cells will certainly speed up development of applications over the next 10 years.
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Transforming pluripotency: an exon-level study of malignancy-specific transcripts in human embryonal carcinoma and embryonic stem cells.
Sharmini Alagaratnam,Neil J. Harrison,Anne Cathrine Bakken,Andreas M. Hoff,Mark Jones,Anita Sveen,Harry Moore,Peter W. Andrews,Ragnhild A. Lothe,Rolf Inge Skotheim +9 more
TL;DR: To circumvent difficulties of isolating pure populations of cancer stem cells (CSCs) for the purpose of identifying malignancy-specific gene expression, exon-resolution transcriptomic profiles of 5 embryonal carcinoma (EC) cell lines are compared to their nonmalignant caricature, specifically 6 human embryonic stem (ES) cell Lines.