P
Peter W. Andrews
Researcher at University of Sheffield
Publications - 286
Citations - 22367
Peter W. Andrews is an academic researcher from University of Sheffield. The author has contributed to research in topics: Embryonic stem cell & Cellular differentiation. The author has an hindex of 71, co-authored 280 publications receiving 21323 citations. Previous affiliations of Peter W. Andrews include East Sussex County Council & Wistar Institute.
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Journal ArticleDOI
Prepatterning in the Stem Cell Compartment
Peter D. Tonge,Victor Olariu,Daniel Coca,Visakan Kadirkamanathan,Kelly Burrell,Stephen A. Billings,Peter W. Andrews +6 more
TL;DR: The results suggest that pluripotent NTERA2 stem cells oscillate between functionally distinct substates that are primed to select distinct lineages when differentiation is induced.
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Importance of a new tumor marker TRA-1-60 in the follow-up of patients with clinical stage I nonseminomatous testicular germ cell tumors
M. E. Gels,J Marrink,P Visser,Dirk Sleijfer,J. H. J. Droste,Harald J. Hoekstra,Peter W. Andrews,H. Schraffordt Koops +7 more
TL;DR: The combination of AFP, hCG, and TRA-1-60 may improve the early detection of recurrence and be useful in the follow-up of stage I NSTGCT.
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Differentiation antigens of human germ cell tumours: distribution of carbohydrate epitopes on glycolipids and glycoproteins analyzed using PDMP, an inhibitor of glycolipid synthesis.
TL;DR: Resistance to PDMP inhibition suggests that glycoproteins carry the immunodominant form of SSEA1 on the cell surface of differentiated human EC cells and undifferentiated murine EC cells.
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Pinacidil enhances survival of cryopreserved human embryonic stem cells.
TL;DR: Pinacidil has been used for many years as a vasodilator drug to treat hypertension and its manufacture and traceability are well defined and it is also considerably cheaper than Y-27632, so the use of pinacidil offers an efficient method for recovery of cryopreserved dissociated human ES cells.
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Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells.
Thomas F. Allison,Andrew J.H. Smith,Andrew J.H. Smith,Konstantinos Anastassiadis,Jackie Sloane-Stanley,Veronica Biga,Dylan Stavish,James O.S. Hackland,Shan Sabri,Justin Langerman,Mark Jones,Kathrin Plath,Daniel Coca,Ivana Barbaric,Paul J. Gokhale,Peter W. Andrews +15 more
TL;DR: It is confirmed that substates characterized by expression of GATA6 and SSEA3 include pluripotent stem cells capable of long-term self-renewal and a potential role for SOX17 in the establishment of the endoderm-biased stem cell state.