P
Philip Schulman
Researcher at North Shore University Hospital
Publications - 25
Citations - 4594
Philip Schulman is an academic researcher from North Shore University Hospital. The author has contributed to research in topics: CD5 & Antigen. The author has an hindex of 14, co-authored 25 publications receiving 4459 citations. Previous affiliations of Philip Schulman include University of Genoa & North Shore-LIJ Health System.
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Journal ArticleDOI
Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia.
Rajendra N. Damle,Tarun Wasil,Tarun Wasil,Tarun Wasil,Franco Fais,Franco Fais,Franco Fais,Fabio Ghiotto,Fabio Ghiotto,Fabio Ghiotto,Angelo Valetto,Angelo Valetto,Angelo Valetto,Steven L. Allen,Steven L. Allen,Steven L. Allen,Aby Buchbinder,Aby Buchbinder,Aby Buchbinder,Daniel R. Budman,Daniel R. Budman,Daniel R. Budman,Klaus Dittmar,Klaus Dittmar,Klaus Dittmar,Jonathan E. Kolitz,Jonathan E. Kolitz,Jonathan E. Kolitz,Stuart M. Lichtman,Stuart M. Lichtman,Stuart M. Lichtman,Philip Schulman,Philip Schulman,Philip Schulman,Vincent Vinciguerra,Vincent Vinciguerra,Vincent Vinciguerra,Kanti R. Rai,Kanti R. Rai,Kanti R. Rai,Manlio Ferrarini,Manlio Ferrarini,Manlio Ferrarini,Nicholas Chiorazzi,Nicholas Chiorazzi,Nicholas Chiorazzi +45 more
TL;DR: In this paper, cellular immunophenotypic studies were performed on a cohort of randomly selected IgM(+) B-chronic lymphocytic leukemia (B-CLL) cases for which Ig V(H) and V(L) gene sequences were available.
Journal ArticleDOI
Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.
Franco Fais,Fabio Ghiotto,Shiori Hashimoto,Brian Sellars,Angelo Valetto,Steven L. Allen,Philip Schulman,Vincent Vinciguerra,Kanti R. Rai,Laura Z. Rassenti,Thomas J. Kipps,Guillaume Dighiero,Harry W. Schroeder,Manlio Ferrarini,Nicholas Chiorazzi +14 more
TL;DR: These data suggest that many B-CLL cells have been previously stimulated, placing them in the "experienced" or "memory" CD5(+) B cell subset.
Journal ArticleDOI
B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes.
Rajendra N. Damle,Fabio Ghiotto,Angelo Valetto,Emilia Albesiano,Franco Fais,Xiao-Jie Yan,Cristina Sison,Steven L. Allen,Jonathan E. Kolitz,Philip Schulman,Vincent Vinciguerra,Petra Budde,Jürgen Frey,Kanti R. Rai,Manlio Ferrarini,Nicholas Chiorazzi +15 more
TL;DR: The findings imply that the leukemic cells from all B-CLL cases (irrespective of V gene mutations) exhibit features of activated and of antigen-experienced B lymphocytes and that the B- CLL cells that differ in immunoglobulin V genotype may have different antigen-encounter histories.
Journal ArticleDOI
Production of autoantibodies by CD5-expressing B lymphocytes from patients with chronic lymphocytic leukemia.
Zev M. Sthoeger,Mariko Wakai,D B Tse,Vincent Vinciguerra,Steven L. Allen,Daniel R. Budman,Stuart M. Lichtman,Philip Schulman,Lora Weiselberg,Nicholas Chiorazzi +9 more
TL;DR: CD5-expressing B lymphocytes from patients with selected chronic lymphoproliferative disorders were used to determine whether monoclonal populations of CD5+ human B cells produce autoantibodies, and several react with dsDNA, a specificity not previously reported and often seen in association with significant autoimmune disorders.
Journal Article
Clonal expansion within the CD4+CD57+ and CD8+CD57+ T cell subsets in chronic lymphocytic leukemia.
Davide Serrano,Joanita Monteiro,Steven L. Allen,Jonathan E. Kolitz,Philip Schulman,Stuart M. Lichtman,Aby Buchbinder,Vincent Vinciguerra,Nicholas Chiorazzi,Peter K. Gregersen +9 more
TL;DR: A comprehensive analysis of the CD4+ and CD8+ T cell repertoire in a population of CLL patients and age-matched controls points to a role for clonal T cell populations in the pathogenesis of this disease.