P
Phillip McGuire
Researcher at King's College London
Publications - 66
Citations - 1132
Phillip McGuire is an academic researcher from King's College London. The author has contributed to research in topics: Psychosis & First episode. The author has an hindex of 16, co-authored 66 publications receiving 954 citations. Previous affiliations of Phillip McGuire include South London and Maudsley NHS Foundation Trust & National Council for Scientific and Technological Development.
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Journal ArticleDOI
Tryptophan depletion reduces right inferior prefrontal activation during response inhibition in fast, event-related fMRI.
Katya Rubia,Francis Lee,Anthony J. Cleare,Nigel Tunstall,Cynthia H.Y. Fu,Michael Brammer,Phillip McGuire +6 more
TL;DR: These findings provide neuro-functional evidence of a serotonergic modulation of right inferior prefrontal during inhibitory motor control, and the increased engagement of temporal brain regions may reflect compensatory mechanisms.
Journal ArticleDOI
The Lambeth Early Onset Crisis Assessment Team Study : general practitioner education and access to an early detection team in first-episode psychosis
Paddy Power,E Iacoponi,Nicola Reynolds,Helen L. Fisher,Morris Russell,Philippa Garety,Phillip McGuire,Thomas J. Craig +7 more
TL;DR: Educating GPs improves detection and referral rates of first-episode psychosis patients and an early detection team reduces the long delays in initial assessment and treatment, however, these only impact on the later phases of the DUP.
Journal ArticleDOI
The Promise of Biological Markers for Treatment Response in First-Episode Psychosis: A Systematic Review
Guillaume Fond,Marc Antoine D'Albis,Stéphane Jamain,Ryad Tamouza,Celso Arango,W. Wolfgang Fleischhacker,Birte Glenthøj,Markus Leweke,Shôn Lewis,Phillip McGuire,Andreas Meyer-Lindenberg,Iris E. C. Sommer,Inge van Rossum,Shitij Kapur,René S. Kahn,Dan Rujescu,Marion Leboyer +16 more
TL;DR: A systematic review of trials that assessed biological markers associated with antipsychotic response or side effects in first-episode psychosis and potential biomarkers associated with biological disturbances that may guide the choice of conventional treatments or the prescription of innovative treatments are provided.
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Are cavum septum pellucidum abnormalities more common in schizophrenia spectrum disorders? A systematic review and meta-analysis.
Clarissa Trzesniak,Clarissa Trzesniak,Irismar Reis de Oliveira,Matthew J. Kempton,Amanda Galvão-de Almeida,Amanda Galvão-de Almeida,Marcos Hortes Nisihara Chagas,Maria Cecília Freitas Ferrari,Alaor Santos Filho,Antonio Waldo Zuardi,D. A. Prado,Geraldo F. Busatto,Phillip McGuire,Jaime Eduardo Cecílio Hallak,José Alexandre de Souza Crippa +14 more
TL;DR: Overall the results suggest that only a large CSP is associated with SSD while a small CSP may be considered a normal neuroanatomical variation.
Journal ArticleDOI
The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects.
Jaime Eduardo Cecílio Hallak,Serdar M. Dursun,Serdar M. Dursun,Daniel Carneiro da Cunha Bosi,Ligia Ribeiro Horta de Macedo,Ligia Ribeiro Horta de Macedo,João Paulo Machado-de-Sousa,João Paulo Machado-de-Sousa,João Abrão,José Alexandre de Souza Crippa,José Alexandre de Souza Crippa,Phillip McGuire,Phillip McGuire,John H. Krystal,Glen B. Baker,Glen B. Baker,Antonio Waldo Zuardi,Antonio Waldo Zuardi +17 more
TL;DR: Cannabidiol significantly augmented the activating effects of ketamine, as measured by the activation subscales of the BPRS, however, CBD showed a non-significant trend to reduce ketamine-induced depersonalization, as measures by the CADSS.