P
Ponnampalam Gopalakrishnakone
Researcher at National University of Singapore
Publications - 163
Citations - 5933
Ponnampalam Gopalakrishnakone is an academic researcher from National University of Singapore. The author has contributed to research in topics: Venom & Snake venom. The author has an hindex of 43, co-authored 162 publications receiving 5489 citations. Previous affiliations of Ponnampalam Gopalakrishnakone include University of Louisiana at Monroe & Agency for Science, Technology and Research.
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Journal ArticleDOI
In vitro antimicrobial activity of natural toxins and animal venoms tested against Burkholderia pseudomallei.
R. Perumal Samy,A. Pachiappan,Ponnampalam Gopalakrishnakone,Maung M. Thwin,Yap Eu Hian,Vincent Tk K. Chow,Ho Bow,Joseph T. Weng +7 more
TL;DR: This antibacterial profile of snake venoms reported herein will be useful in the search for potential antibacterial agents against drug resistant microorganisms like B. pseudomallei.
Journal ArticleDOI
Domoic acid-induced neuronal damage in the rat hippocampus: changes in apoptosis related genes (bcl-2, bax, caspase-3) and microglial response.
TL;DR: The results indicate that the pattern of neuronal degeneration observed during DA‐induced excitotoxic damage is mostly necrotic.
Journal ArticleDOI
lambda-conotoxins, a new family of conotoxins with unique disulfide pattern and protein folding. Isolation and characterization from the venom of Conus marmoreus.
R. Ashok Balaji,Atsuko Ohtake,Kazuki Sato,Ponnampalam Gopalakrishnakone,R. Manjunatha Kini,Kah Tong Seow,Boon-Huat Bay +6 more
TL;DR: It appears that the unique disulfide pattern, and hence the "ribbon" conformation, in lambda-conotoxins is important for their biological activity.
Proceedings ArticleDOI
Digital taste and smell communication
Nimesha Ranasinghe,Kasun Karunanayaka,Adrian David Cheok,Owen Noel Newton Fernando,Hideaki Nii,Ponnampalam Gopalakrishnakone +5 more
TL;DR: Sourness and saltiness are the main sensations that could be evoked through this device, which is developed a control system, an actuator, which could digitally stimulate the sense of taste remotely.
Journal ArticleDOI
SCORPION, a molecular database of scorpion toxins
Kellathur N. Srinivasan,Ponnampalam Gopalakrishnakone,Paul T. J. Tan,K.C. Chew,B. Cheng,R.M. Kini,Judice L. Y. Koh,Seng Hong Seah,Vladimir Brusic +8 more
TL;DR: The grouping of scorpion toxins provides a basis for extending and clarifying the existing structural and functional classifications, and the bioinformatics modules in SCORPION facilitate analyses aimed at classification of scorpions toxins and identification of sequence patterns associated with specific structural or functional properties.