P
Ponnampalam Gopalakrishnakone
Researcher at National University of Singapore
Publications - 163
Citations - 5933
Ponnampalam Gopalakrishnakone is an academic researcher from National University of Singapore. The author has contributed to research in topics: Venom & Snake venom. The author has an hindex of 43, co-authored 162 publications receiving 5489 citations. Previous affiliations of Ponnampalam Gopalakrishnakone include University of Louisiana at Monroe & Agency for Science, Technology and Research.
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Purification and partial characterization of stonustoxin (lethal factor) from Synanceja horrida venom.
C.H. Poh,R. Yuen,Hoon Eng Khoo,Maxey C. M. Chung,Matthew C.E. Gwee,Ponnampalam Gopalakrishnakone +5 more
TL;DR: The lethal factor of the stonefish venom, designated as the stonustoxin, was purified to homogeneity by a two-step procedure on Sephacryl S-200 High Resolution gel permeation and DEAE Bio-Gel A anion exchange chromatography to show potent haemolytic activity in vitro and edema-inducing activity in vivo.
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Practical integration of polymerase chain reaction amplification and electrophoretic analysis in microfluidic devices for genetic analysis.
Isabel Rodriguez,Marie L Lesaicherre,Yan Tie,Quanbo Zou,Chen Yu,Janak Singh,Lim Tit Meng,Sridhar Uppili,Sam Fong Yau Li,Ponnampalam Gopalakrishnakone,Zachariah E. Selvanayagam +10 more
TL;DR: Genomic DNA samples from several bird species such as pigeon and chicken were analyzed and the integrated μPCR‐μchip for the identification of bird sex was tested, showing that the system could be used as well to determine the sex of avian species.
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Cytoskeletal Rearrangements in Synovial Fibroblasts as a Novel Pathophysiological Determinant of Modeled Rheumatoid Arthritis
Vassilis Aidinis,Piero Carninci,Maria Armaka,Walter Witke,Vaggelis Harokopos,Norman Pavelka,Dirk Koczan,Christos Argyropoulos,Maung Maung Thwin,Steffen Möller,Waki Kazunori,Ponnampalam Gopalakrishnakone,Paola Ricciardi-Castagnoli,Hans Jürgen Thiesen,Yoshihide Hayashizaki,George Kollias +15 more
TL;DR: The gelsolin-driven synovial fibroblast cytoskeletal rearrangements as a novel pathophysiological determinant of the disease is identified through the integration of genetic linkage analysis and Gene Ontology–assisted functional discovery.
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Sites of action of mojave toxin isolated from the venom of the mojave rattlesnake
Ponnampalam Gopalakrishnakone,Barbara J. Hawgood,S.E. Holbrooke,N.A. Marsh,S. Santana De Sa,Anthony T. Tu +5 more
TL;DR: Mojave toxin showed antigenic similarities to crotoxin, the lethal neurotoxin in the venom of the South American rattlesnake, as determined by the ability of antiserum raised against crot toxin to neutralize Mojave toxin.
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Sensing the future of HCI: touch, taste, and smell user interfaces
Marianna Obrist,Carlos Velasco,Chi Thanh Vi,Nimesha Ranasinghe,Ali Israr,Adrian David Cheok,Charles Spence,Ponnampalam Gopalakrishnakone +7 more
TL;DR: Digital Taste Interface is a method for simulating the sensation of taste by actuating the human tongue through electrical and thermal stimulation, and Taste+ is an interface where the user can augment the flavors of food and beverages by applying weak and controlled electrical pulses on their tongue using electronically enhanced everyday utensils.