P
Pontus Gourdon
Researcher at University of Copenhagen
Publications - 72
Citations - 2447
Pontus Gourdon is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 22, co-authored 54 publications receiving 1894 citations. Previous affiliations of Pontus Gourdon include University of Gothenburg & National Research Foundation of South Africa.
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Journal ArticleDOI
Light stimulates growth of proteorhodopsin-containing marine Flavobacteria
Laura Gómez-Consarnau,José M. González,Montserrat Coll-Lladó,Pontus Gourdon,Torbjörn Pascher,Richard Neutze,Carlos Pedrós-Alió,Jarone Pinhassi +7 more
TL;DR: The results show that the phototrophy conferred by proteorhodopsin can provide critical amounts of energy, not only for respiration and maintenance but also for active growth of marine bacterioplankton in their natural environment.
Journal ArticleDOI
Crystal structure of a copper-transporting PIB-type ATPase.
Pontus Gourdon,Xiangyu Liu,Xiangyu Liu,Tina Skjørringe,J. Preben Morth,J. Preben Morth,Lisbeth Birk Møller,Bjørn Panyella Pedersen,Bjørn Panyella Pedersen,Poul Nissen +9 more
TL;DR: The structure of a PIB-ATPase, a Legionella pneumophila CopA Cu+-ATpase, in a copper-free form, is presented, as determined by X-ray crystallography at 3.2 Å resolution, and indicates a three-stage copper transport pathway involving several conserved residues.
Journal ArticleDOI
Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema
Philip Kitchen,Mootaz M. Salman,Mootaz M. Salman,Mootaz M. Salman,Andrea M. Halsey,Charlotte Clarke-Bland,Justin A. MacDonald,Hiroaki Ishida,Hans J. Vogel,Sharif Almutiri,Sharif Almutiri,Ann Logan,Stefan Kreida,Tamim Al-Jubair,Julie Winkel Missel,Pontus Gourdon,Pontus Gourdon,Susanna Törnroth-Horsefield,Matthew T. Conner,Zubair Ahmed,Alex C. Conner,Roslyn M. Bill +21 more
TL;DR: It is shown that AQP4 cell-surface abundance increases in response to hypoxia-induced cell swelling in a calmodulin-dependent manner, and it is proposed that targeting the mechanism of cal modulin-mediated cell- surface localization of AQP 4 is a viable strategy for development of CNS edema therapies.
Journal ArticleDOI
Crystal Structure of Na+, K+-ATPase in the Na+-Bound State
Maria Nyblom,Maria Nyblom,Hanne Poulsen,Hanne Poulsen,Hanne Poulsen,Pontus Gourdon,Pontus Gourdon,Pontus Gourdon,Linda Reinhard,Linda Reinhard,Magnus Andersson,Erik Lindahl,Erik Lindahl,Natalya U. Fedosova,Natalya U. Fedosova,Poul Nissen,Poul Nissen,Poul Nissen +17 more
TL;DR: The crystal structure of a Na+-bound Na+, K+-ATPase is presented, which reveals conformational changes associated with Na+ binding and the location of three bound sodium ions and the mechanism of sodium release in a key plasma membrane ion pump are revealed.
Journal ArticleDOI
Crystal Structure of an Ammonia-Permeable Aquaporin.
Andreas Kirscht,Shreyas S. Kaptan,Gerd Patrick Bienert,Gerd Patrick Bienert,François Chaumont,Poul Nissen,Bert L. de Groot,Per Kjellbom,Pontus Gourdon,Urban Johanson +9 more
TL;DR: By mutational studies, it is shown that the identified determinants in the extended selectivity filter region are sufficient to convert a strictly water-specific human aquaporin into an AtTIP2;1-like ammonia channel.