Prema

TL;DR: Two new quassinoids, (16R)-methoxyjavanicin B (1) and (16S)- methoxy javanic in B (2), along with seven known compounds, were isolated during the phytochemical investigation of the CHCl3 soluble portion of the MeOH extract of P. javanica wood.

TL;DR: Four new labdane diterpenoids isolated from the methanol extract of Curcuma amada rhizomes collected in Myanmar showed strong antiproliferative activities selectively against HeLa, PANC-1, and PSN-1 cells, and their potencies were comparable to those of the positive control, 5-fluorouracil.

TL;DR: It is demonstrated that the furofuran and dioxymethylene moieties of the lignans play a vital role in inhibiting melanogenesis.

TL;DR: The anti-HIV-1 viral protein R (Vpr) assay revealed that 1 and 2 exhibited potent anti-Vpr activities at 1.25 μM, and revealed the potentAnti-VPR activities of (16R)-methoxyjavanicin B (7) and (16S)- methoxyJavanic in B (8), which were previously isolated from the Picrasma javanica wood.

TL;DR: Three new lignoids, premnan A (1), premnan B (2), and tauntangyiol C (3), were isolated from Premna serratifolia wood and tested for their melanogenesis activities against the B16-F10 mouse melanoma cell line, without any cytotoxicity.