Qijing Bo

TL;DR: It is found that default mode network functional connectivity remains a prime target for understanding the pathophysiology of depression, with particular relevance to revealing mechanisms of effective treatments, and reduced rather than increased FC within the DMN is found.

TL;DR: PHQ-9 showed good reliability and validity, and high adaptability for patients with MDD in psychiatric hospital, and is a simple, rapid, effective, and reliable tool for screening and evaluation of the severity of depression.

TL;DR: The results showed that the pairwise values of the MAMs between the ACC and the amygdala, insula, precuneus, and thalamus were significantly lower in patients with MDD compared to those in HC.

TL;DR: Patients who continued to receive the full risperidone dose used for their acute episode had fewer relapses than those who had dose reductions after 4 weeks or 26 weeks during the maintenance period and experienced greater reduction in the severity of psychotic symptoms.

TL;DR: Cognitive deficits in domains of processing speed and working memory are prominent in patients with bipolar disorder and the findings suggest that MCCB can be usefully applied in BD.