Yonggui Yuan

TL;DR: It is found that default mode network functional connectivity remains a prime target for understanding the pathophysiology of depression, with particular relevance to revealing mechanisms of effective treatments, and reduced rather than increased FC within the DMN is found.

TL;DR: This study provides direct evidence for the association of a great majority of convergent and a minority of divergent connectivity of WM structural networks between RGD and aMCI patients, which may lead to increasing attention in defining a population at risk of AD.

TL;DR: The impairment of posterior cingulate and precuneus could be an important marker to distinguish aMCI from healthy aging in the resting-state and the increased regional homogeneity changes would be consistent with compensation for damage to the medial temporal regions and limbic structures, perhaps by recruitment of alternative regions.

TL;DR: Resting-state connectivity disturbance of PCC-temporal cortex may be a central role in cognitive deficit in aMCI patients and this would be consonant with the recruitment of compensatory mechanisms and the process of offset functional impairments appearing as neuropathologic develops.

TL;DR: Early changes in functional connectivity involving the hippocampus may yield important new data to predict whether a patient will eventually develop AD, because aMCI is a putative prodromal syndrome to Alzheimer's disease (AD).