R.J. Leer

TL;DR: The 3,308,274-bp sequence of the chromosome of Lactobacillus plantarum strain WCFS1, a single colony isolate of strain NCIMB8826 that was originally isolated from human saliva, has been determined, and contains 3,052 predicted protein-encoding genes, suggesting that these genes form a lifestyle adaptation region in the chromosome.

TL;DR: Analysis of mucosal induction of pro- and anti-inflammatory cytokines, IgA-producing plasma cells in the gut, as well as systemic antibody responses against a parenterally administered antigen suggests that rational Lactobacillus strain selection provides a strategy to influence cytokine expression and thereby influence immune responses.

TL;DR: Vectors encoding a single-chain Fv (scFv) antibody fragment, which recognizes the streptococcal antigen I/II (SAI/II) adhesion molecule of Streptococcus mutans, were constructed and expressed in Lactobacilli zeae and fused to an E-tag.

TL;DR: An overview is given of current research aimed at unravelling the relationship between structure and properties of surface proteins of lactobacilli and in vivo colonization, in particular of species capable of adhering to epithelial cells in vitro.

TL;DR: Lactobacillus vectors are generally rapidly lost when cells are cultivated in the absence of selective pressure, however, pLPE323 is stable in three of four LactOBacillus strains tested so far and is most likely to be explained by the incompatibility of the vectors and resident plasmids.