R
R M Maiorino
Researcher at University of Arizona
Publications - 30
Citations - 1394
R M Maiorino is an academic researcher from University of Arizona. The author has contributed to research in topics: Arsenic & Toxaphene. The author has an hindex of 22, co-authored 30 publications receiving 1373 citations.
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Journal ArticleDOI
Mobilization of heavy metals by newer, therapeutically useful chelating agents
H. Vasken Aposhian,R M Maiorino,Diego Gonzalez-Ramirez,Miguel Angel Zúñiga-Charles,Zhao-Fa Xu,Katherine M. Hurlbut,Pablo Junco-Munoz,Richard C. Dart,Mary M. Aposhian +8 more
TL;DR: The Dimaval-mercury challenge test holds great promise as a diagnostic test for mercury exposure, especially for low level mercurialism.
Journal ArticleDOI
DMPS-arsenic challenge test. II. Modulation of arsenic species, including monomethylarsonous acid (MMAIII), excreted in human urine.
H. Vasken Aposhian,Baoshan Zheng,Mary M. Aposhian,X. Chris Le,Mariano E. Cebrián,William R. Cullen,Robert A. Zakharyan,Mingsheng Ma,Richard C. Dart,Zhai Cheng,Zhai Cheng,Paul Andrewes,Luke Yip,Gerald F. O'Malley,R M Maiorino,Wayne A. Van Voorhies,Sheila M. Healy,Allison Titcomb +17 more
TL;DR: The experimental results support the hypothesis that DMPS competes with endogenous ligands for MMA(III), forming a DMPS-MMA complex that is readily excreted in the urine and points out the need for studying the biochemical toxicology of MMA( III).
Journal ArticleDOI
DMSA, DMPS, and DMPA--as arsenic antidotes.
TL;DR: In this paper, the relative effectiveness or therapeutic index of these compounds in protecting mice from the lethal effects of an LD99 of sodium arsenite is DMSA greater than DMPS, DMPA more than DMPA, and N-(2,3-dimercaptopropyl )-phthalamidic acid (DMPA) greater than BAL in the magnitude of 42:14:4:1, respectively.
Journal ArticleDOI
Human studies with the chelating agents, DMPS and DMSA
H. Vasken Aposhian,R M Maiorino,Mario Rivera,David C. Bruce,Richard C. Dart,Katherine M. Hurlbut,Deborah Levine,Wei Zheng,Quintus Fernando,Dean E. Carter,Mary M. Aposhian +10 more
TL;DR: There was a positive correlation between the amount of mercury excreted and the amalgam score and DMPS might be useful for increasing the urinary excretion of mercury and thus increasing the significance and reliability of this measure of mercury exposure.
Journal Article
Sodium 2,3-dimercaptopropane-1-sulfonate challenge test for mercury in humans: II. Urinary mercury, porphyrins and neurobehavioral changes of dental workers in Monterrey, Mexico
Diego Gonzalez-Ramirez,R M Maiorino,M Zuniga-Charles,Zhao-Fa Xu,Katherine M. Hurlbut,P Junco-Munoz,Mary M. Aposhian,Richard C. Dart,J H Diaz Gama,D Echeverria +9 more
TL;DR: The easily performed DMPS-mercury challenge test is useful for monitoring dental personnel for mercury vapor exposure and is a better indicator of exposure and renal mercury burden than is the mercury level measured in the urine before DMPS is given.