R
Rafael Molina
Researcher at University of Barcelona
Publications - 46
Citations - 2528
Rafael Molina is an academic researcher from University of Barcelona. The author has contributed to research in topics: CA 15-3 & Carcinoembryonic antigen. The author has an hindex of 25, co-authored 46 publications receiving 2282 citations.
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Journal ArticleDOI
National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for Use of Tumor Markers in Testicular, Prostate, Colorectal, Breast, and Ovarian Cancers
Catharine M. Sturgeon,Michael J. Duffy,Ulf-Håkan Stenman,Hans Lilja,Nils Brünner,Daniel W. Chan,Richard J. Babaian,Robert C. Bast,Barry L. Dowell,Francisco J. Esteva,Caj Haglund,Nadia Harbeck,Daniel F. Hayes,Mads Nikolaj Holten-Andersen,George G. Klee,Rolf Lamerz,Leendert H. J. Looijenga,Rafael Molina,Hans Jørgen Nielsen,Harry G. Rittenhouse,Axel Semjonow,Ie Ming Shih,Paul Sibley,György Sölétormos,Carsten Stephan,Lori J. Sokoll,Barry Hoffman,Eleftherios P. Diamandis +27 more
TL;DR: Recommendations to encourage optimal use of tumor markers for 5 cancer sites were critically reviewed and alpha-fetoprotein, human chorionic gonadotropin, and lactate dehydrogenase are recommended for diagnosis/case finding, staging, prognosis determination, recurrence detection, and therapy monitoring.
Journal ArticleDOI
Comparison of Serum Human Epididymis Protein 4 with Cancer Antigen 125 as a Tumor Marker in Patients with Malignant and Nonmalignant Diseases
TL;DR: HE4 has significantly higher diagnostic specificity than CA 125, and the combination of CA 125 and HE4 improved the detection of ovarian cancer in all stages and histological types.
Journal ArticleDOI
HE4 a novel tumour marker for ovarian cancer: comparison with CA 125 and ROMA algorithm in patients with gynaecological diseases.
Rafael Molina,Jose M. Escudero,Jose M. Auge,Xavier Filella,Laura Foj,Aureli Torné,J.A. Lejarcegui,Jaume Pahisa +7 more
TL;DR: Evaluation of a new tumour marker, HE4, in comparison with CA 125 and the Risk of Ovarian Malignancy Algorithm in healthy women and in patients with benign and malignant gynaecological diseases indicates that ROMA algorithm might be further improved if it is used only in Patients with normal HE4 and abnormal CA 125 serum levels.
Journal ArticleDOI
Validation of New Cancer Biomarkers: A Position Statement from the European Group on Tumor Markers
Michael J. Duffy,Catharine M. Sturgeon,György Sölétormos,Vivian Barak,Rafael Molina,Daniel F. Hayes,Eleftherios P. Diamandis,Patrick M.M. Bossuyt +7 more
TL;DR: Application of the methodology outlined above should result in a more efficient and effective approach to the development of cancer biomarkers as well as the reporting of cancer cancer biomarker studies.
Journal ArticleDOI
Mucins CA 125, CA 19.9, CA 15.3 and TAG-72.3 as tumor markers in patients with lung cancer: comparison with CYFRA 21-1, CEA, SCC and NSE.
Rafael Molina,Jose M. Auge,Jose M. Escudero,Ramon M. Marrades,Nuria Viñolas,Emilio Carcereny,José Ramírez,Xavier Filella +7 more
TL;DR: Tumor markers may be useful in the histological differentiation of NSCLC and SCLC, and using a combination of 3 tumor markers, a high sensitivity may be achieved in all histological types.