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Rafael Radi

Researcher at University of the Republic

Publications -  342
Citations -  31694

Rafael Radi is an academic researcher from University of the Republic. The author has contributed to research in topics: Peroxynitrite & Nitric oxide. The author has an hindex of 92, co-authored 319 publications receiving 28403 citations. Previous affiliations of Rafael Radi include Medical College of Wisconsin & University of Pittsburgh.

Papers
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Journal ArticleDOI

Mechanistic studies of peroxynitrite-mediated tyrosine nitration in membranes using the hydrophobic probe N-t-BOC-L-tyrosine tert-butyl ester.

Silvina Bartesaghi, +7 more
- 13 May 2006 - 
TL;DR: BTBE was successfully applied as a hydrophobic probe to study nitration mechanisms and will serve to study factors controlling protein and lipid nitration in biomembranes and lipoproteins.
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Detection and quantification of nitric oxide-derived oxidants in biological systems.

Matías N. Möller, +5 more
- 04 Oct 2019 - 
TL;DR: The biologically relevant characteristics of the reactive species formed downstream from NO• are described, and the approaches currently available for the analysis of NO•, nitrogen dioxide (NO2•), dinitrogen trioxide (N2O3), nitroxyl (HNO), and peroxynitrite (ONOO−/ONOOH) are discussed.
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Formation of protein tyrosine ortho-semiquinone radical and nitrotyrosine from cytochrome c-derived tyrosyl radical.

Yeong Renn Chen, +6 more
- 23 Apr 2004 - 
TL;DR: Investigation of oxidative alteration of mitochondrial cytochrome c after exposure to NO in the presence of H2O2 revealed the formation of 3-nitrotyrosine, indicating that it is peroxynitrite-independent, and the endothelium relaxant factor nitric oxide is well known to mediate mitochondrial respiration and apoptosis.
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Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes.

Krisztian Stadler, +6 more
- 15 Sep 2008 - 
TL;DR: These studies support inducible nitric oxide synthase as a significant source of EPR-detectable reactive intermediates, which leads to lipid peroxidation and may contribute to disease progression as well.
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Neurovascular coupling in hippocampus is mediated via diffusion by neuronal-derived nitric oxide

Cátia F. Lourenço, +5 more
- 01 Aug 2014 - 
TL;DR: Measurements of nitric oxide dynamics and CBF changes in hippocampus in vivo support the notion that during glutamatergic activation nNOS-derived NO induces a time, space, and amplitude-coupled increase in the local CBF, later followed by a transient increase in local O2 tension.