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Randall T. Moon

Researcher at University of Washington

Publications -  305
Citations -  54792

Randall T. Moon is an academic researcher from University of Washington. The author has contributed to research in topics: Wnt signaling pathway & Signal transduction. The author has an hindex of 119, co-authored 305 publications receiving 51964 citations. Previous affiliations of Randall T. Moon include Marine Biological Laboratory & Howard Hughes Medical Institute.

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Journal ArticleDOI

Tissue-specific expression of distinct spectrin and ankyrin transcripts in erythroid and nonerythroid cells.

Randall T. Moon, +3 more
- 01 Jan 1985 - 
TL;DR: Observations suggest that independent gene regulation and tissue-specific production of heterogeneous transcripts from the beta spectrin and ankyrin genes underlie the formation of distinct membrane skeletons in erythroid and muscle cells.
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Changes in the expression of alpha-fodrin during embryonic development of Xenopus laevis.

D H Giebelhaus, +3 more
- 01 Aug 1987 - 
TL;DR: Results suggest that the synthesis of alpha-fodrin polypeptides during embryonic development of Xenopus is regulated, rather than constitutive, and that the primary level of control is the steady-state abundance of mRNA.
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The Wnt/β-catenin Pathway

Randall T. Moon
- 05 Aug 2003 - 
TL;DR: This work has shown that activation of this pathway shows promise as a target for developing osteoporosis, neurodegenerative disease, and stem cell therapies, and inhibiting this pathway in transformed cells shows promise for anticancer therapies.
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TC1(C8orf4) Correlates with Wnt/β-Catenin Target Genes and Aggressive Biological Behavior in Gastric Cancer

Byung-Sik Kim, +10 more
- 01 Jun 2006 - 
TL;DR: TC1 enhanced Matrigel invasiveness and proliferation, supporting its role in the aggressive biological behavior of cancers, suggested that TC1 could be a potential therapeutic target of advanced gastric cancers.
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Dissecting Wnt signalling pathways and Wnt-sensitive developmental processes through transient misexpression analyses in embryos of Xenopus laevis.

Randall T. Moon, +8 more
- 01 Dec 1993 - 
TL;DR: In this paper, the authors review evidence that Xenopus Wnts (Xwnts) have activities consistent with their hypothesized roles as secreted signalling factors involved in multiple developmental processes including changes in gap junctional permeability, altered responsiveness to growth factors, and possibly changes in cell adhesion.