L
Louise E. Glover
Researcher at Anschutz Medical Campus
Publications - 69
Citations - 4399
Louise E. Glover is an academic researcher from Anschutz Medical Campus. The author has contributed to research in topics: Medicine & Inflammation. The author has an hindex of 28, co-authored 57 publications receiving 3454 citations. Previous affiliations of Louise E. Glover include University of Colorado Denver & Harvard University.
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Journal ArticleDOI
Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function
Caleb J. Kelly,Leon Zheng,Eric L. Campbell,Bejan Saeedi,Carsten C. Scholz,Amanda Bayless,Kelly Wilson,Louise E. Glover,Douglas J. Kominsky,Aaron Magnuson,Tiffany L. Weir,Stefan F. Ehrentraut,Stefan F. Ehrentraut,Christina Pickel,Kristine A. Kuhn,Jordi M. Lanis,Vu Nguyen,Cormac T. Taylor,Sean P. Colgan +18 more
TL;DR: A mechanism where host-microbe interactions augment barrier function in the distal gut is highlighted, where the influences of butyrate are lost in cells lacking HIF, thus linkingbutyrate metabolism to stabilized HIF and barrier function.
Journal ArticleDOI
Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
Eric T. Clambey,Eóin N. McNamee,Joseph A. Westrich,Louise E. Glover,Eric L. Campbell,Paul Jedlicka,Edwin F. de Zoeten,John C. Cambier,Kurt R. Stenmark,Sean P. Colgan,Holger K. Eltzschig +10 more
TL;DR: It is demonstrated that hypoxia is an intrinsic molecular cue that promotes FoxP3 expression, in turn eliciting potent anti-inflammatory mechanisms to limit tissue damage in conditions of reduced oxygen availability.
Journal ArticleDOI
Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation
Eric L. Campbell,Walter J. Bruyninckx,Caleb J. Kelly,Louise E. Glover,Eóin N. McNamee,Brittelle E. Bowers,Amanda J. Bayless,Melanie Scully,Bejan Saeedi,Lucy Golden-Mason,Stefan F. Ehrentraut,Valerie F. Curtis,Adrianne Burgess,John F. Garvey,Amber Sorensen,Raphael A. Nemenoff,Paul Jedlicka,Cormac T. Taylor,Douglas J. Kominsky,Sean P. Colgan +19 more
TL;DR: In this paper, the authors investigated the contribution of neutrophils and respiratory burst to inflammatory hypoxia and effective inflammatory resolution in a colitis model using HIF-inducible factor (HIF) mice.
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Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification
Eric L. Campbell,Christopher F. MacManus,Douglas J. Kominsky,Simon Keely,Louise E. Glover,Brittelle E. Bowers,M Scully,Walter J. Bruyninckx,Sean P. Colgan +8 more
TL;DR: Administration of RvE1 resulted in significant improvement of disease activity indices concomitant with increased ALPI expression in the intestinal epithelium, and inhibition of ALPI activity resulted in increased severity of colitis in DSS-treated animals and partially abrogated the protective influence of R vE1.
Journal ArticleDOI
Dysferlin in membrane trafficking and patch repair.
Louise E. Glover,Robert H. Brown +1 more
TL;DR: Dysferlin is the first identified member of a putative muscle‐specific repair complex that permits rapid resealing of membranes disrupted by mechanical stress and the evolving picture of dysferlin‐related signaling pathways in muscle cell physiology and pathology is outlined.