R
Rebecca M. Pruss
Researcher at National Institutes of Health
Publications - 67
Citations - 3779
Rebecca M. Pruss is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Olesoxime & Enkephalin. The author has an hindex of 32, co-authored 67 publications receiving 3617 citations. Previous affiliations of Rebecca M. Pruss include Marion Merrell Dow.
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Journal ArticleDOI
Neuropeptide Y and peptide YY neuronal and endocrine systems.
Thomas L. O'Donohue,Bibie M. Chronwall,Rebecca M. Pruss,Eva Mezey,J Z Kiss,Lee E. Eiden,V.J. Massari,Richard E. Tessel,Virginia M. Pickel,Debora A. DiMaggio +9 more
TL;DR: Evidence has been presented which indicates that NPY may play important roles in regulating autonomic function, and the peptide coexists with catecholamines in the central and sympathetic nervous system and adrenal medulla.
Journal ArticleDOI
Variants of 3T3 cells lacking mitogenic response to epidermal growth factor
TL;DR: Of the eight clonal EGF nonresponder variants selected by this procedure, none retains a functional EGF receptor and the EGFnonresponsive va-riant lines still retain the ability to respond to other mitogens.
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Identification and Characterization of Cholest-4-en-3-one, Oxime (TRO19622), a Novel Drug Candidate for Amyotrophic Lateral Sclerosis
Thierry Bordet,Bruno Buisson,Magali Michaud,Cyrille Drouot,Pascale Galéa,Pierre Delaage,Natalia P. Akentieva,Alex S. Evers,Douglas F. Covey,Mariano A. Ostuni,Jean-Jacques Lacapère,Charbel Massaad,Michael Schumacher,Esther-Marie Steidl,Delphine Maux,Michel Delaage,Christopher E. Henderson,Rebecca M. Pruss +17 more
TL;DR: In vivo and in vitro, TRO19622 rescued motor neurons from axotomy-induced cell death in neonatal rats and promoted nerve regeneration following sciatic nerve crush in mice, suggesting a potential mechanism for its neuroprotective activity.
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Characterization of (2S,4R)-1-[5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a Selective and Orally Active Vasopressin V1b Receptor Antagonist
Claudine Serradeil-Le Gal,Jean Wagnon,Jacques Simiand,Guy Griebel,Colette Lacour,Gilles Guillon,Claude Barberis,Gabrielle Brossard,Philippe Soubrie,D. Nisato,Marc Pascal,Rebecca M. Pruss,Bernard Scatton,J P Maffrand,Gérard Le Fur +14 more
TL;DR: SSR149415 is a potent, selective, and orally active V1b receptor antagonist and deserves to be clinically investigated in the field of stress and anxiety.
Agonist-Activated Cobalt Uptake Identifies Divalent Cation-Permeable
TL;DR: Pruss et al. as mentioned in this paper found that activation of kainate receptors causes Co*+ influx into neurons, type-2 astrocytes, and 0-2A progenitor cells.