R
Richard A. Lafayette
Researcher at Stanford University
Publications - 138
Citations - 5056
Richard A. Lafayette is an academic researcher from Stanford University. The author has contributed to research in topics: Nephropathy & Medicine. The author has an hindex of 32, co-authored 111 publications receiving 3970 citations. Previous affiliations of Richard A. Lafayette include Massachusetts Institute of Technology & Mayo Clinic.
Papers
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Journal ArticleDOI
Renal Physiology of Pregnancy
TL;DR: The kidneys increase in length and volume, and physiologic hydronephrosis occurs in up to 80% of women, which is fundamental in caring for the pregnant patient.
Journal ArticleDOI
Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass.
TL;DR: The results indicate that the effects of converting enzyme inhibition on remnant glomerular function and structure depend on reduction in AII activity and are not attributable simply to normalization of systemic blood pressure.
Journal ArticleDOI
Podocytopenia and disease severity in IgA nephropathy.
Kevin V. Lemley,Richard A. Lafayette,Massy Safai,Geraldine C. Derby,Kristina Blouch,Addy Squarer,Bryan D. Myers +6 more
TL;DR: The findings show that podocyte loss is a concomitant of increasing disease severity in IgA nephropathy, which suggests that podocytes loss may either cause or contribute to the progressive proteinuria, glomerular sclerosis and filtration failure seen in this disorder.
Journal ArticleDOI
Rituximab or Cyclosporine in the Treatment of Membranous Nephropathy
Fernando C. Fervenza,Gerald B. Appel,Sean J. Barbour,Brad H. Rovin,Richard A. Lafayette,Nabeel Aslam,Jonathan Ashley Jefferson,Patrick E. Gipson,Dana V. Rizk,John R. Sedor,James F. Simon,Ellen T. McCarthy,Paul Brenchley,Sanjeev Sethi,Carmen Avila-Casado,Heather Beanlands,John C. Lieske,David Philibert,Tingting Li,Tingting Li,Lesley F. Thomas,Dolly F. Green,Luis A. Juncos,Lada Beara-Lasic,Samuel S. Blumenthal,Amy N. Sussman,Stephen B. Erickson,Michelle Hladunewich,Pietro A. Canetta,Lee A. Hebert,Nelson Leung,Jay Radhakrishnan,Heather N. Reich,Samir V. Parikh,Debbie S. Gipson,Dominic K. Lee,Bruno R. da Costa,Peter Jüni,Daniel C Cattran +38 more
TL;DR: Rituximab was noninferior to cyclosporine in inducing complete or partial remission of proteinuria at 12 months and was superior in maintaining proteinuria remission up to 24 months.
Journal ArticleDOI
Pathophysiology of the Clinical Manifestations of Preeclampsia
TL;DR: The potential that changes in soluble angiogenic factors may underlie much of the disease process is considered, on the basis of the observation that the only definitive cure for preeclampsia is delivery of the placenta and that women who experience a molar pregnancy frequently develop severe preeClampsia.