R
Richard Colling
Researcher at University of Oxford
Publications - 59
Citations - 781
Richard Colling is an academic researcher from University of Oxford. The author has contributed to research in topics: Medicine & Digital pathology. The author has an hindex of 12, co-authored 43 publications receiving 432 citations. Previous affiliations of Richard Colling include Bristol Royal Infirmary & John Radcliffe Hospital.
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Journal ArticleDOI
Artificial intelligence in digital pathology: a roadmap to routine use in clinical practice.
Richard Colling,Helen Pitman,Karin A. Oien,Nasir M. Rajpoot,Philip S. Macklin,David Snead,Tony Sackville,Clare Verrill +7 more
TL;DR: There is a clear need for a robust and evidence‐based framework in which to develop these new tools in a collaborative manner that meets regulatory approval, and a roadmap to help academia, industry, and clinicians develop new software tools to the point of approved clinical use is set out.
Journal ArticleDOI
Deep learning for detecting tumour-infiltrating lymphocytes in testicular germ cell tumours
Nina Linder,Jenny C. Taylor,Richard Colling,Robert Pell,Edward Alveyn,Johnson Joseph,Andrew Protheroe,Mikael Lundin,Johan Lundin,Clare Verrill +9 more
TL;DR: Deep learning–based image analysis can be used for detecting TILs in testicular germ cell cancer more objectively and it has potential for use as a prognostic marker for disease relapse.
Journal ArticleDOI
Spatially resolved clonal copy number alterations in benign and malignant tissue
Andrew Erickson,Mengxiao He,Emelie Berglund,Maja Marklund,Reza Mirzazadeh,Niklas Schultz,Linda Kvastad,Alma Andersson,Ludvig Bergenstråhle,Joseph Bergenstråhle,Ludvig Larsson,Leire Alonso Galicia,Alia Shamikh,Elisa Basmaci,Teresita Díaz de Ståhl,Timothy Rajakumar,Dimitrios Doultsinos,Kim Thrane,Andrew L. Ji,Paul A. Khavari,Firaz Tarish,Anna Tanoglidi,Jonas Maaskola,Richard Colling,Tuomas Mirtti,Freddie C. Hamdy,Dan J. Woodcock,Thomas Helleday,Ian G. Mills,Alastair D. Lamb,Joakim Lundeberg +30 more
TL;DR: In this paper , the authors used spatially resolved transcriptomics to infer spatial copy number variations in 120,000 regions across multiple organs, in benign and malignant tissues, and demonstrate that genome-wide copy number variation reveals distinct clonal patterns within tumours and in nearby benign tissue using an organ-wide approach focused on the prostate.
Journal ArticleDOI
Digital pathology and artificial intelligence will be key to supporting clinical and academic cellular pathology through COVID-19 and future crises: the PathLAKE consortium perspective.
Lisa Browning,Richard Colling,Emad A. Rakha,Nasir M. Rajpoot,Jens Rittscher,Jacqueline A James,Manuel Salto-Tellez,David Snead,Clare Verrill +8 more
TL;DR: The specific impact of COVID-19 on clinical and academic pathology and how digital pathology and artificial intelligence can play a key role to safeguarding clinical services and pathology-based research in the current climate and in the future are explored.
Journal ArticleDOI
Multi-Center Evaluation of the Fully Automated PCR-Based Idylla™ KRAS Mutation Assay for Rapid KRAS Mutation Status Determination on Formalin-Fixed Paraffin-Embedded Tissue of Human Colorectal Cancer
Jérôme Solassol,Julie A. Vendrell,Bruno Märkl,Christian J. Haas,Beatriz Bellosillo,Clara Montagut,Matthew Smith,Brendan O'Sullivan,Nicky D'Haene,Marie Le Mercier,Morten Grauslund,Linea Cecilie Melchior,Emma Burt,Finbarr E. Cotter,Daniel Stieber,Fernando de Lander Schmitt,Valentina Motta,Calogero Lauricella,Richard Colling,Elizabeth J. Soilleux,Matteo Fassan,Claudia Mescoli,Christine Collin,Jean-Christophe Pages,Peter Sillekens +24 more
TL;DR: The Idylla™ KRAS Mutation Test can be applied as routine tool in any clinical setting, without needing molecular infrastructure or expertise, to guide the personalized treatment of colorectal cancer patients.