R
Rita Haapakoski
Researcher at Finnish Institute of Occupational Health
Publications - 19
Citations - 1431
Rita Haapakoski is an academic researcher from Finnish Institute of Occupational Health. The author has contributed to research in topics: Proinflammatory cytokine & Immunoglobulin E. The author has an hindex of 13, co-authored 19 publications receiving 1127 citations. Previous affiliations of Rita Haapakoski include University College London & University of Oulu.
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Journal ArticleDOI
Cumulative meta-analysis of interleukins 6 and 1β, tumour necrosis factor α and C-reactive protein in patients with major depressive disorder
Rita Haapakoski,Rita Haapakoski,Rita Haapakoski,Julia Mathieu,Klaus P. Ebmeier,Harri Alenius,Mika Kivimäki +6 more
TL;DR: This meta-analysis confirms a robust link between IL-6, CRP and major depression and the role of TNF-α and IL-1β in major depression remains uncertain.
Journal ArticleDOI
Innate and adaptive immunity in the development of depression: An update on current knowledge and technological advances.
TL;DR: It is highlighted how combining basic immune methods with more advanced ‘omics’ technologies would help to make progress in unravelling the complex associations between altered immune function and depressive disorders, in the identification of depression-specific biomarkers and in developing immunotherapeutic treatment strategies that take individual variability into account.
Journal ArticleDOI
Study protocol: the Whitehall II imaging sub-study
Nicola Filippini,Eniko Zsoldos,Rita Haapakoski,Claire E. Sexton,Abda Mahmood,Charlotte L. Allan,Anya Topiwala,Vyara Valkanova,Eric J. Brunner,Martin J. Shipley,Edward J. Auerbach,Steen Moeller,Kamil Ugurbil,Junqian Xu,Junqian Xu,Essa Yacoub,Jesper L. R. Andersson,Janine D. Bijsterbosch,Stuart Clare,Ludovica Griffanti,Aaron T. Hess,Mark Jenkinson,Karla L. Miller,Gholamreza Salimi-Khorshidi,Stamatios N. Sotiropoulos,Natalie L. Voets,Stephen M. Smith,John R. Geddes,Archana Singh-Manoux,Archana Singh-Manoux,Clare E. Mackay,Mika Kivimäki,Klaus P. Ebmeier +32 more
TL;DR: The integration of cutting-edge MRI techniques, clinical and cognitive tests in combination with retrospective data on social, behavioural and biological variables from a well-established longitudinal epidemiological study (WHII cohort) will provide a unique opportunity to examine brain structure and function in relation to age-related diseases and the modifiable and non-modifiable factors affecting resilience against and vulnerability to adverse brain changes.
Journal ArticleDOI
Assessment of the Neuropeptide S System in Anxiety Disorders
Jonas Donner,Rita Haapakoski,Sini Ezer,Erik Melén,Erik Melén,Sami Pirkola,Sami Pirkola,Mònica Gratacòs,Marco Zucchelli,Marco Zucchelli,Francesca Anedda,Francesca Anedda,Lovisa E. Johansson,Cilla Söderhäll,Christina Orsmark-Pietras,Christina Orsmark-Pietras,Jaana Suvisaari,Rocío Martín-Santos,Marta Torrens,Kaisa Silander,Joseph D. Terwilliger,Joseph D. Terwilliger,Magnus Wickman,Magnus Wickman,Göran Pershagen,Jouko Lönnqvist,Jouko Lönnqvist,Leena Peltonen,Xavier Estivill,Mauro D'Amato,Mauro D'Amato,Juha Kere,Harri Alenius,Iiris Hovatta,Iiris Hovatta +34 more
TL;DR: In this paper, the role of NPS and NPSR1 as susceptibility genes for human anxiety disorders was investigated and the most significantly associated single nucleotide polymorphisms altered DNA-protein complex formation in electrophoretic mobility shift assays.
Assessment of the Neuropeptide S System in Anxiety Disorders
Jonas Donner,Rita Haapakoski,Sini Ezer,Erik Melén,Erik Melén,Sami Pirkola,Sami Pirkola,Mònica Gratacòs,Marco Zucchelli,Marco Zucchelli,Francesca Anedda,Francesca Anedda,Lovisa E. Johansson,Cilla Söderhäll,Christina Orsmark-Pietras,Christina Orsmark-Pietras,Jaana Suvisaari,Rocío Martín-Santos,Marta Torrens,Kaisa Silander,Joseph D. Terwilliger,Joseph D. Terwilliger,Magnus Wickman,Magnus Wickman,Göran Pershagen,Jouko Lönnqvist,Jouko Lönnqvist,Leena Peltonen,Xavier Estivill,Mauro D'Amato,Mauro D'Amato,Juha Kere,Harri Alenius,Iiris Hovatta,Iiris Hovatta +34 more
TL;DR: The results suggest that NPS-NPSR1 signaling is likely involved in anxiety and confirmed previously observed epidemiological association between anxiety and asthma in two population-based cohorts.