R
Robert McKenna
Researcher at University of Florida
Publications - 481
Citations - 23708
Robert McKenna is an academic researcher from University of Florida. The author has contributed to research in topics: Carbonic anhydrase & Carbonic anhydrase II. The author has an hindex of 78, co-authored 457 publications receiving 21349 citations. Previous affiliations of Robert McKenna include University of South Carolina & Florida State University College of Arts and Sciences.
Papers
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Journal ArticleDOI
Cellular and molecular characterization of two novel asparagine synthetase gene mutations linked to asparagine synthetase deficiency
Stephen Staklinski,M.C.Y. Chang,Fang Yu,Kathleen Collins Ruff,David Neal Franz,Zhijian Qian,Linda B. Bloom,H. Merritt,Robert McKenna,Michael S. Kilberg +9 more
TL;DR: In this paper , the authors describe a compound heterozygotic ASNSD child with two novel mutations in the ASNS gene, c.1118G>T (paternal) and c.1556G>A (maternal), that lead to G373V or R519H variants.
Journal ArticleDOI
Substrate-dependent interference of carbonic anhydrases with the glutamine transporter SNAT3-induced conductance.
TL;DR: This study shows that this conductance of rat SNAT3, expressed in Xenopus oocytes, is also suppressed following co-expression with CAI, CAIII, CAIV, and CAII-H64A (mutant with impaired intramolecular H+ shuttling), and hypothesized that this substrate specificity of the CA action might be due to the different ion selectivity induced by the different amino acid substrates, which induce currents carried by sodium and/or protons.
Book ChapterDOI
Chapter 16 – Engineered Mammalian Carbonic Anhydrases for CO2 Capture
TL;DR: This chapter describes the use and production of kinetically enhanced and/or thermostabilized CA variants to aid in the development of proficient and economical CO 2 capture systems.
Journal Article
Post-mastectomy angiosarcoma: case report and review of the literature.
Journal ArticleDOI
Microbatch Mixing: “Shaken not Stirred”, a Method for Macromolecular Microcrystal Production for Serial Crystallography
Brian P. Mahon,Justin J. Kurian,Carrie L. Lomelino,Ian R. Smith,Lilien Socorro,Antonette Bennett,Alex M. Hendon,Paul R. Chipman,Daniel A. Savin,Mavis Agbandje-McKenna,Robert McKenna +10 more
TL;DR: Labeled microbatch mixing (MBM) as mentioned in this paper was proposed to produce large quantities of microcrystals of macromolecules suitable for serial crystallographic experiments and has been shown to be successful for producing lysozyme, carbonic anhydrase and adeno-associated virus crystals.