R
Robert McKenna
Researcher at University of Florida
Publications - 481
Citations - 23708
Robert McKenna is an academic researcher from University of Florida. The author has contributed to research in topics: Carbonic anhydrase & Carbonic anhydrase II. The author has an hindex of 78, co-authored 457 publications receiving 21349 citations. Previous affiliations of Robert McKenna include University of South Carolina & Florida State University College of Arts and Sciences.
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Cloning, expression, purification, crystallization and preliminary X-ray analysis of Mycoplasma genitalium protein MG289.
Katherine H. Sippel,Susan K. Boehlein,Yoshihisa Sakai,Jeanne G. Quirit,Mavis Agbandje-McKenna,Charles J. Rosser,Robert McKenna +6 more
TL;DR: The crystal structure of Cypl, the ortholog of MG289 from M. hyorhinis, has recently been determined, providing a reasonable phasing model; molecular replacement is currently under way.
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Small Molecule Alkoxy Oriented Selectiveness on Human Carbonic Anhydrase II and IX Inhibition
Murat Bozdag,Lochlin D Cravey,Jacob Combs,Anusha Kota,Robert McKenna,Andrea Angeli,Silvia Selleri,Fabrizio Carta,Claudiu T. Supuran +8 more
TL;DR: This study adds to the field of developing hCA inhibitors at molecular level the critical interactions governing ligand selectivity by investigating in vitro the inhibition potency of aryl sulfonamide inhibitors of human carbonic anhydrase enzymes containing short ureido alkoxy tails.
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Validation of the lung cancer staging system revisions using a large prospective clinical trial database (ACOSOG Z0030).
Juan J. Fibla,Stephen D. Cassivi,Paul A. Decker,Mark S. Allen,Gail Darling,Rodney J. Landreneau,Robert McKenna,David R. Jones,Richard Inculet,Joe B. Putnam +9 more
TL;DR: This study sought to test the validity of this new system on a separate prospectively collected cohort of patients from a recent multicenter trial of early-stage lung cancer, and found that TNM descriptors and overall staging were valid.