R
Robert McKenna
Researcher at University of Florida
Publications - 481
Citations - 23708
Robert McKenna is an academic researcher from University of Florida. The author has contributed to research in topics: Carbonic anhydrase & Carbonic anhydrase II. The author has an hindex of 78, co-authored 457 publications receiving 21349 citations. Previous affiliations of Robert McKenna include University of South Carolina & Florida State University College of Arts and Sciences.
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Journal ArticleDOI
Evidence-based criteria to help distinguish metastatic breast cancer from primary lung adenocarcinoma on thoracic frozen section.
TL;DR: A differential diagnosis model composed of significant pathologic features that favor the diagnosis of primary lung adenocarcinoma or metastatic breast carcinoma or both was identified and successfully tested by challenging 19 pathologists and trainees with a test set of 20 unknown FSs, supporting the clinical applicability of the diagnostic model.
Book ChapterDOI
Overview of the Carbonic Anhydrase Family
Robert McKenna,Susan C. Frost +1 more
TL;DR: This book is by no means fully inclusive, as only a few of the lead researchers around the world contributed; it serves only to show that the CA field is still pushing the boundaries of research as it has done since its discovery, and will do for a long time to come.
Journal ArticleDOI
Preliminary investigation of the phage φX174 crystal structure
Peter Willingmann,Sankaran Krishnaswamy,Robert McKenna,Thomas J. Smith,Norman H. Olson,Michael G. Rossmann,Patricia L. Stow,Nino L. Incardona +7 more
TL;DR: In this paper, a single-stranded DNA bacteriophage φX174 has been grown and the mean diameter of the virus particles is 280 A. Packing considerations show that the virus separates into two bands in a sucrose gradient, but both bands contain intact particles.
Journal ArticleDOI
An intramolecular lock facilitates folding and stabilizes the tertiary structure of Streptococcus mutans adhesin P1.
Kyle P. Heim,Paula J. Crowley,Joanna R. Long,Shweta Kailasan,Robert McKenna,L. Jeannine Brady +5 more
TL;DR: A stable complex of recombinant N- and C-terminal fragments is cocrystallized and the structure reveals that the N terminus forms a stabilizing scaffold by wrapping behind the base of P1’s elongated stalk and physically “locking” it into place.
Journal ArticleDOI
Tracking solvent and protein movement during CO2 release in carbonic anhydrase II crystals.
Chae Un Kim,Chae Un Kim,Hyojjin Song,Balendu Sankara Avvaru,Sol M. Gruner,SangYoun Park,Robert McKenna +6 more
TL;DR: Structural “snapshots” of hCA II intermediate states are provided for the first time, to the authors' knowledge, during the formation of the His64-mediated proton wire that is induced as CO2 is released.