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Robert McKenna

Researcher at University of Florida

Publications -  481
Citations -  23708

Robert McKenna is an academic researcher from University of Florida. The author has contributed to research in topics: Carbonic anhydrase & Carbonic anhydrase II. The author has an hindex of 78, co-authored 457 publications receiving 21349 citations. Previous affiliations of Robert McKenna include University of South Carolina & Florida State University College of Arts and Sciences.

Papers
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Journal ArticleDOI

Innovative approaches to lung volume reduction for emphysema.

Matthew Brenner, +5 more
- 01 Jul 2004 - 
TL;DR: Concepts being actively investigated at this time include surgical resection with compression/banding devices, endobronchial blockers, sealants, obstructing devices and valves, and bronchial bypass methods.
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Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action

Alessandro Bonardi, +11 more
- 10 Jun 2020 - 
TL;DR: The most active and selective inhibitors against isoforms implicated in glaucoma were assessed in a rabbit model of the disease achieving an intraocular pressure-lowering action comparable to the clinically used dorzolamide.
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p37 induces tumor invasiveness

Catherine M Ketcham, +9 more
- 01 Jul 2005 - 
TL;DR: Recombinant p37 enhanced the invasiveness of two prostate carcinoma and two melanoma cell lines in a dose-dependent manner in vitro, but did not have a significant effect on tumor cell growth.
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Chemical rescue in catalysis by human carbonic anhydrases II and III.

Haiqian An, +7 more
- 05 Mar 2002 - 
TL;DR: The data suggest that the out position of His 64 considered alone is not active in proton transfer in HCA II, and the difference in the susceptibility of CA II and III to chemical rescue may be related to the more sterically constrained and electrostatically positive nature of the active site cavity of CA III compared with CA II.
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Structural analysis of the spiroplasma virus, SpV4: implications for evolutionary variation to obtain host diversity among the Microviridae

Paul R. Chipman, +4 more
- 15 Feb 1998 - 
TL;DR: Sequence alignment and structural analysis indicate that distinct genera of the Microviridae might have evolved from a common primordial ancestor, with capsid surface variations, such as the SpV4 protrusions, resulting from gene fusion events that have enabled diverse host ranges.