Roberto Antolović

TL;DR: Sodium pump inhibitor B from bovine adrenals is the cardenolide ouabain, which shows properties similar to the proscillaridin A immunoreactivity that increased in humans with systolic blood pressure and pulse pressure.

TL;DR: Docking study showed that flavonoids bind to the BChE active site by forming multiple hydrogen bonds and pi-pi interactions, and UV-VIS absorption spectra of the flavonoid phosphate buffer solution revealed time dependant changes indicating precipitation of Flavonoids or in the case of myricetin, a change in the chemical structure resulting in a BChChE non-inhibiting specie.

TL;DR: A novel class of antibiotic compounds—macrolones, which are derived from macrolides and comprise macrocyclic moiety, linker, and either free or esterified quinolone 3-carboxylic group, show excellent antibacterial potency towards key erythromycin-resistant Gram-positive and Gram-negative bacterial strains, with possibly decreased potential of bacterial resistance to macrolide antibiotics.

TL;DR: Right-side-out vesicles of pig kidney microsomes and amino-acid-sequence-specific antibodies were used to probe the sidedness of the C- terminus and the N-terminus of the catalytic alpha subunit of Na+/K(+)-ATPase.

TL;DR: The three-dimensional structure of Fyn tyrosine kinase, a Src-family enzyme involved in T-cell receptor signal transduction, is presented and it is revealed that Fyn is inhibited by a linear-mixed noncompetitive mechanism of inhibition by rosmarinic acid.