R
Robyn R. Raban
Researcher at University of California, San Diego
Publications - 21
Citations - 549
Robyn R. Raban is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Aedes aegypti & Gene drive. The author has an hindex of 8, co-authored 16 publications receiving 290 citations. Previous affiliations of Robyn R. Raban include Colorado State University & University of California, Berkeley.
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Journal ArticleDOI
Development of a confinable gene drive system in the human disease vector Aedes aegypti
Ming Li,Ting Yang,Nikolay P. Kandul,Michelle Bui,Stephanie Gamez,Robyn R. Raban,Jared B. Bennett,M C Héctor Sánchez,Gregory C. Lanzaro,Hanno Schmidt,Yoosook Lee,John M. Marshall,Omar S. Akbari +12 more
TL;DR: Several CRISPR-based split gene drives are developed for use in Ae.
Journal ArticleDOI
Fitness impact and stability of a transgene conferring resistance to dengue-2 virus following introgression into a genetically diverse Aedes aegypti strain.
Alexander W. E. Franz,Irma Sanchez-Vargas,Robyn R. Raban,William C. Black,Anthony A. James,Ken E. Olson +5 more
TL;DR: Although minimal fitness loss was manifest in the final family selection stage, the authors were able to select homozygotes for the transgene in one family, Carb109M/GDLS, which has been genetically stable and refractory to DENV2 for >33 generations.
Posted ContentDOI
Development of a Confinable Gene-Drive System in the Human Disease Vector, Aedes aegypti.
Ming Li,Ting Yang,Nikolay P. Kandul,Michelle Bui,Stephanie Gamez,Robyn R. Raban,Jared B. Bennett,M C Héctor Sánchez,Gregory C. Lanzaro,Hanno Schmidt,Yoosook Lee,John M. Marshall,Omar S. Akbari +12 more
TL;DR: Several CRISPR-based split-gene drives are engineered and tested and provide compelling path forward for the feasibility of future effector-linked split-drive technologies that can contribute to the safe, sustained control and potentially the elimination of pathogens transmitted by this species.
Journal ArticleDOI
Combating mosquito-borne diseases using genetic control technologies.
Guan-Hong Wang,Guan-Hong Wang,Stephanie Gamez,Robyn R. Raban,John M. Marshall,Luke Alphey,Ming Li,Jason L. Rasgon,Omar S. Akbari +8 more
TL;DR: A review of the latest developments, notable similarities, and critical distinctions between these promising technologies and discuss their future applications for mosquito-borne disease control can be found in this paper, where the authors discuss the future applications of these technologies.
Journal ArticleDOI
Progress towards engineering gene drives for population control
TL;DR: Recent progress has brought us closer than ever before to genetic-based vector modification as a tool to support vector-borne disease elimination efforts worldwide.