H
Hanno Schmidt
Researcher at University of California, Davis
Publications - 36
Citations - 1457
Hanno Schmidt is an academic researcher from University of California, Davis. The author has contributed to research in topics: Population & Genome. The author has an hindex of 14, co-authored 29 publications receiving 1153 citations. Previous affiliations of Hanno Schmidt include Goethe University Frankfurt & University of California, Berkeley.
Papers
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Journal ArticleDOI
Corrigendum: Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.
Xiaodong Fang,Eviatar Nevo,Lijuan Han,Erez Y. Levanon,Jing Zhao,Aaron Avivi,Denis M. Larkin,Xuanting Jiang,Sergey Feranchuk,Yabing Zhu,Alla Fishman,Yue Feng,Noa Sher,Zhiqiang Xiong,Thomas Hankeln,Zhiyong Huang,Vera Gorbunova,Lu Zhang,Wei Zhao,Derek E. Wildman,Derek E. Wildman,Yingqi Xiong,Andrei V. Gudkov,Qiumei Zheng,Gideon Rechavi,Sanyang Liu,Lily Bazak,Jie Chen,Jie Chen,Binyamin A. Knisbacher,Yao Lu,Imad Shams,Krzysztof Gajda,Marta Farré,Jaebum Kim,Harris A. Lewin,Jian Ma,Mark Band,Anne Bicker,Angela Kranz,Tobias Mattheus,Hanno Schmidt,Andrei Seluanov,Jorge Azpurua,Michael R. McGowen,Eshel Ben Jacob,Kexin Li,Shaoliang Peng,Xiaoqian Zhu,Xiangke Liao,Shuai Cheng Li,Anders Krogh,Xin Zhou,Leonid Brodsky,Jun Wang +54 more
TL;DR: In this paper, a Genome-Wide Adaptive Complex to underground stresses in blind mole rats Spalax is described, where the adaptive complexes are based on adaptive complexes to underground stress.
Journal ArticleDOI
Next-generation gene drive for population modification of the malaria vector mosquito, Anopheles gambiae.
Rebeca Carballar-Lejarazú,Christian E. Ogaugwu,Christian E. Ogaugwu,Taylor Tushar,Adam Kelsey,Thai Binh Pham,Jazmin Murphy,Hanno Schmidt,Yoosook Lee,Gregory C. Lanzaro,Anthony A. James +10 more
TL;DR: It is shown here that the Cas9/guide RNA-based gene-drive components of a genetically-engineered malaria mosquito vector, Anopheles gambiae, achieve key target product profile requirements for efficacy and performance.
Journal ArticleDOI
Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax
Xiaodong Fang,Eviatar Nevo,Lijuan Han,Erez Y. Levanon,Jing Zhao,Aaron Avivi,Denis M. Larkin,Xuanting Jiang,Sergey Feranchuk,Yabing Zhu,Alla Fishman,Yue Feng,Noa Sher,Zhiqiang Xiong,Thomas Hankeln,Zhiyong Huang,Vera Gorbunova,Lu Zhang,Wei Zhao,Derek E. Wildman,Yingqi Xiong,Andrei V. Gudkov,Qiumei Zheng,Gideon Rechavi,Sanyang Liu,Lily Bazak,Jie Chen,Binyamin A. Knisbacher,Yao Lu,Imad Shams,Krzysztof Gajda,Marta Farré,Jaebum Kim,Harris A. Lewin,Jian Ma,Mark Band,Anne Bicker,Angela Kranz,Tobias Mattheus,Hanno Schmidt,Andrei Seluanov,Jorge Azpurua,Michael R. McGowen,Eshel Ben Jacob,Kexin Li,Shaoliang Peng,Xiaoqian Zhu,Xiangke Liao,Shuai Cheng Li,Anders Krogh,Xin Zhou,Leonid Brodsky,Jun Wang,Jun Wang +53 more
TL;DR: The results show high rates of RNA/DNA editing, reduced chromosome rearrangements, an over-representation of short interspersed elements (SINEs) probably linked to Hypoxia tolerance, degeneration of vision and progression of photoperiodic perception, tolerance to hypercapnia and hypoxia and resistance to cancer.
Journal ArticleDOI
Development of a confinable gene drive system in the human disease vector Aedes aegypti
Ming Li,Ting Yang,Nikolay P. Kandul,Michelle Bui,Stephanie Gamez,Robyn R. Raban,Jared B. Bennett,M C Héctor Sánchez,Gregory C. Lanzaro,Hanno Schmidt,Yoosook Lee,John M. Marshall,Omar S. Akbari +12 more
TL;DR: Several CRISPR-based split gene drives are developed for use in Ae.
Posted ContentDOI
Development of a Confinable Gene-Drive System in the Human Disease Vector, Aedes aegypti.
Ming Li,Ting Yang,Nikolay P. Kandul,Michelle Bui,Stephanie Gamez,Robyn R. Raban,Jared B. Bennett,M C Héctor Sánchez,Gregory C. Lanzaro,Hanno Schmidt,Yoosook Lee,John M. Marshall,Omar S. Akbari +12 more
TL;DR: Several CRISPR-based split-gene drives are engineered and tested and provide compelling path forward for the feasibility of future effector-linked split-drive technologies that can contribute to the safe, sustained control and potentially the elimination of pathogens transmitted by this species.