R
Rodrigo Cabrera
Researcher at Del Rosario University
Publications - 18
Citations - 189
Rodrigo Cabrera is an academic researcher from Del Rosario University. The author has contributed to research in topics: Schizosaccharomyces & Medicine. The author has an hindex of 4, co-authored 13 publications receiving 165 citations. Previous affiliations of Rodrigo Cabrera include National University of Colombia & Baylor College of Medicine.
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Journal ArticleDOI
The eIF3 interactome reveals the translasome, a supercomplex linking protein synthesis and degradation machineries.
Zhe Sha,Laurence M. Brill,Rodrigo Cabrera,Oded Kleifeld,Judith S. Scheliga,Michael H. Glickman,Eric C. Chang,Dieter A. Wolf +7 more
TL;DR: The data reveal the breadth of the eIF3 interactome and suggest that factors involved in translation initiation, ribosome biogenesis, translation elongation, quality control, and transport are physically linked to facilitate efficient protein synthesis.
Journal ArticleDOI
Proteasome nuclear import mediated by Arc3 can influence efficient DNA damage repair and mitosis in Schizosaccharomyces pombe.
Rodrigo Cabrera,Zhe Sha,Tegy J. Vadakkan,Joel H Otero,Franziska Kriegenburg,Rasmus Hartmann-Petersen,Mary E. Dickinson,Eric C. Chang +7 more
TL;DR: In this article, the authors have isolated a subunit of the Arp2/3 complex, Arc3, which binds proteasomes and showed that proteasome nuclear import is reduced when Arc3 is inactivated, leading to hypersensitivity to DNA damage and inefficient cyclin-B degradation.
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Schizosaccharomyces pombe Arc3 is a conserved subunit of the Arp2/3 complex required for polarity, actin organization, and endocytosis.
TL;DR: It is suggested that Arc3p is an evolutionarily conserved subunit of the Arp2/3 complex required for proper F‐actin organization and efficient endocytosis.
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Identification of a New Candidate Locus for Ebstein Anomaly in 1p36.2
Marta-Catalina Miranda-Fernández,Silvia Ramírez-Oyaga,Carlos Martín Restrepo,Victor-Manuel Huertas-Quiñones,Victor-Manuel Huertas-Quiñones,Magally Barrera-Castañeda,Rossi Quero,Camilo-José Hernández-Toro,Claudia Tamar Silva,Paul Laissue,Rodrigo Cabrera +10 more
TL;DR: The data suggest that a distal locus containing the SKI gene and a proximal locuscontaining the CHD-associated genes RERE and UBE4B are the most probable etiological factors for EA in patients with 1p36 deletion syndrome.
Journal ArticleDOI
Semiconductor Whole Exome Sequencing for the Identification of Genetic Variants in Colombian Patients Clinically Diagnosed with Long QT Syndrome
TL;DR: The results show that WES can identify LQTS-causing mutations and permits differential diagnosis of related conditions in a real-world clinical setting, however, high heterogeneity in sequencing depth and low coverage in the most relevant genes is expected to be associated with reduced analytical sensitivity.