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Ronald J. Voll
Researcher at Emory University
Publications - 70
Citations - 1190
Ronald J. Voll is an academic researcher from Emory University. The author has contributed to research in topics: Dopamine transporter & Serotonin transporter. The author has an hindex of 19, co-authored 68 publications receiving 1115 citations. Previous affiliations of Ronald J. Voll include Yerkes National Primate Research Center.
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Journal ArticleDOI
Development of a unique small molecule modulator of CXCR4.
Zhongxing Liang,Weiqiang Zhan,Aizhi Zhu,Younghyoun Yoon,Songbai Lin,Maiko Sasaki,Jan-Michael A. Klapproth,Hua Yang,Hans E. Grossniklaus,Jianguo Xu,Mauricio Rojas,Ronald J. Voll,Mark M. Goodman,Richard F. Arrendale,Jin Liu,C. Chris Yun,James P. Snyder,Dennis C. Liotta,Hyunsuk Shim +18 more
TL;DR: A novel small molecule, MSX-122, is developed that is a partial CXCR4 antagonist without mobilizing stem cells, which can be safer for long-term blockade of metastasis than other reported CX CR4 antagonists.
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Improved synthesis of anti-[18F]FACBC: improved preparation of labeling precursor and automated radiosynthesis
TL;DR: An improved synthesis of the precursor of anti-[18F]FACBC has been devised which demonstrates high stereoselectivity and suitability for large-scale preparations, and the major non-radioactive species present in doses of anti- 1-amino-3-hydroxycyclobutane-1-carboxylic acid has been identified.
Journal Article
Initial human PET imaging studies with the dopamine transporter ligand 18F-FECNT.
Margaret R. Davis,John R. Votaw,J. Douglas Bremner,Michael G. Byas-Smith,Tracy L. Faber,Ronald J. Voll,John M. Hoffman,Scott T. Grafton,Clinton D. Kilts,Mark M. Goodman +9 more
TL;DR: In this article, an initial assessment of the usefulness of 2β-carbomethoxy-3β-(4-chlorophenyl)-8-(2-18F-fluoroethyl)nortropane (18F -FECNT) PET scanning in determining in vivo brain dopamine transporter (DAT) density in healthy humans and subjects with Parkinson's disease (PD).
Journal ArticleDOI
Interaction of isoflurane with the dopamine transporter.
John R. Votaw,Michael G. Byas-Smith,Jian Hua,Ronald J. Voll,Laurent Martarello,Allan I. Levey,F. DuBois Bowman,Mark M. Goodman +7 more
TL;DR: In vitro experiments indicate that DAT is trafficked into the cell by isoflurane without changing the total amount of DAT in the striatum, and the PET data are consistent with this finding, provided that intracellular DAT acquires a conformation that has low affinity for [18F]FECNT.
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Synthesis and evaluation of two 18F-labeled imidazo[1,2-a]pyridine analogues as potential agents for imaging β-amyloid in Alzheimer’s disease
Fanxing Zeng,Jeanine A. Southerland,Ronald J. Voll,John R. Votaw,Lawrence E. Williams,Brian J. Ciliax,Allan I. Levey,Mark M. Goodman +7 more
TL;DR: Two new fluorinated imidazo[1,2-a]pyridine derivatives, 6-(2'-fluoroethyl)-2-(4'-dimethylamino)phenylimidazo(FEPIP) and FPPIP, were synthesized and their binding affinity to amyloid plaques in human AD cortical tissues was determined.