R
Rork Kuick
Researcher at University of Michigan
Publications - 166
Citations - 17557
Rork Kuick is an academic researcher from University of Michigan. The author has contributed to research in topics: Gene & Gene expression profiling. The author has an hindex of 60, co-authored 166 publications receiving 16459 citations. Previous affiliations of Rork Kuick include University of Florida.
Papers
More filters
Journal ArticleDOI
EZH2 is overexpressed in Adrenocortical Carcinoma and is associated with disease progression.
Coralie Drelon,Annabel Berthon,Annabel Berthon,Mickael Mathieu,Bruno Ragazzon,Rork Kuick,Houda Tabbal,Amandine Septier,Stéphanie Rodriguez,M. Batisse-Lignier,Isabelle Sahut-Barnola,T. Dumontet,Jean Christophe Pointud,Anne Marie Lefrançois-Martinez,Silvère Baron,Thomas J. Giordano,Jérôme Bertherat,Antoine Martinez,Pierre Val +18 more
TL;DR: Observations suggest that overexpression of EZH2 is associated with aggressive progression and may constitute an interesting therapeutic target in the context of ACC.
Journal ArticleDOI
Data base analysis of protein expression patterns during T-cell ontogeny and activation.
Samir M. Hanash,John R. Strahler,Yang-Hao Chan,Rork Kuick,Daniel Teichroew,James V. Neel,Nabil Hailat,Nabil Hailat,David R. Keim,David R. Keim,Jeanne Gratiot-Deans,David R. Ungar,R. Melhem,Xiang Xiao Zhu,Philip C. Andrews,Friedrich Lottspeich,Christoph Eckerskorn,Ernest H. Y. Chu,I. Ali,David A. Fox,Bruce C. Richardson,Laurence A. Turka +21 more
TL;DR: The identity of several constitutively expressed or mitotically induced proteins in lymphoid cells was established by microsequencing and point to significant differences in the molecular pathways leading to proliferation between mature and immature T cells.
Journal ArticleDOI
Identification of two related markers for common acute lymphoblastic leukemia as heat shock proteins.
John R. Strahler,Rork Kuick,Christoph Eckerskorn,F. Lottspeich,Bruce C. Richardson,David A. Fox,Lloyd M. Stoolman,Curtis A. Hanson,D. Nichols,H. J. Tueche +9 more
TL;DR: Evidence is provided that two polypeptides designated L2 and L4 are structurally related and represent novel markers for common ALL.
Journal ArticleDOI
Proteomic analysis of eIF-5A in lung adenocarcinomas
Guoan Chen,Tarek G. Gharib,Dafydd G. Thomas,Chiang Ching Huang,David E. Misek,Rork Kuick,Thomas J. Giordano,Mark D. Iannettoni,Mark B. Orringer,Samir M. Hanash,David G. Beer +10 more
TL;DR: Higher eIF‐5A protein expression was present in tumors showing poor differentiation, 12/13th codon K‐ras mutations, p53 nuclear accumulation, and tumors with positive lymphocytic response suggesting the use of eIF-5A as prognostic marker in lung adenocarcinoma is suggested.
Journal ArticleDOI
Transforming properties of a Q18→E mutation of the microtubule regulator Op18
David E. Misek,Christina L. Chang,Rork Kuick,Robert Hinderer,Thomas J. Giordano,David G. Beer,Samir M. Hanash +6 more
TL;DR: The mutant form of Op18 (M-Op18) was cloned and sequenced, revealing a substitution of a G for C at nucleotide 155 that results in a Q18-->E substitution in the protein.