R
Rosalinde Masereeuw
Researcher at Utrecht University
Publications - 275
Citations - 10179
Rosalinde Masereeuw is an academic researcher from Utrecht University. The author has contributed to research in topics: Kidney & Organic anion transporter 1. The author has an hindex of 49, co-authored 250 publications receiving 8255 citations. Previous affiliations of Rosalinde Masereeuw include Tohoku University & Katholieke Universiteit Leuven.
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Journal ArticleDOI
Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules
TL;DR: The unique structure, regulation and dual localisation of MRP4 in polarised cells could be connected with a key function in cellular protection and extracellular signalling pathways.
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The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane
Miriam Huls,Colin D.A. Brown,Amy S. Windass,Rachel Sayer,J. J. M. W. van den Heuvel,Suzanne Heemskerk,Frans G. M. Russel,Rosalinde Masereeuw +7 more
TL;DR: Clear localization of BCRP/ABCG2 to the proximal tubule brush border membrane of the human kidney is found comparable to that of other ABC transporters such as P-glycoprotein/ABCB1, MRP2/ ABCC2, and MRP4/ABCC4.
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Tubuloids derived from human adult kidney and urine for personalized disease modeling
Frans Schutgens,Frans Schutgens,Maarten B. Rookmaaker,Thanasis Margaritis,Anne C. Rios,Carola Ammerlaan,Carola Ammerlaan,Jitske Jansen,Linda Gijzen,Marianne K. Vormann,Annelotte M. Vonk,Marco C. Viveen,Fjodor A. Yousef Yengej,Fjodor A. Yousef Yengej,Sepide Derakhshan,Karin M. de Winter-de Groot,Benedetta Artegiani,Ruben van Boxtel,Edwin Cuppen,Antoni P. A. Hendrickx,Marry M. van den Heuvel-Eibrink,Ellen Heitzer,Henriëtte L. Lanz,Jeffrey M. Beekman,Jean-Luc Murk,Rosalinde Masereeuw,Frank C. P. Holstege,Jarno Drost,Marianne C. Verhaar,Hans Clevers +29 more
TL;DR: Conditions for the long-term growth of primary kidney tubular epithelial organoids, or ‘tubuloids’, are described and tubuloids grown from human kidney tissue and urine aid the study of BK virus infection, Wilms tumors and cystic fibrosis.
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Kidney-on-a-Chip Technology for Drug-Induced Nephrotoxicity Screening
Martijn J. Wilmer,Chee Ping Ng,Henriëtte L. Lanz,Paul Vulto,Laura Suter-Dick,Rosalinde Masereeuw +5 more
TL;DR: The application of state-of-the-art microfluidic culturing techniques, with a focus on culturing kidney proximal tubules, that are promising for the detection of biomarkers that predict drug interactions and DIKI are addressed.
Journal ArticleDOI
Renal Toxicity of Radiolabeled Peptides and Antibody Fragments: Mechanisms, Impact on Radionuclide Therapy, and Strategies for Prevention
Erik Vegt,Marion de Jong,Jack F.M. Wetzels,Rosalinde Masereeuw,Marleen Melis,Wim J.G. Oyen,Martin Gotthardt,Otto C. Boerman +7 more
TL;DR: An overview of renal handling of radiolabeled peptides and resulting nephrotoxicity is presented, and strategies to reduce neph rotoxicity are discussed.