Rosella Mechelli

TL;DR: A higher number of Tregs were found in AChR-MG, but a severe functional defect in their regulatory activity was found together with a decreased expression of the FOXP3, PD-L1 and GITR which are essential for T cell regulatory function.

TL;DR: The unprecedented finding of a potential disease-specific role of SNORD13 in Huntington’s disease seems to peripherally report a ‘tipping point’ in the pathogenic cascade at the neuronal level.

TL;DR: C-Glucoside derivatives covalently linked to the arsenic atom in different oxidation states have been synthesized by avoiding protection-deprotection steps as discussed by the authors, which showed promising antiproliferative activity on a cell line of neuroblastoma (SK-N-BE).

TL;DR: The literature regarding the role of metals with supposed pathogenic relevance in MS is reviewed and the peculiar imbalance in serum elements and oxidative status that characterizes CIS people may predict conversion to clinically definite MS.