R
Ryan McClure
Researcher at Pacific Northwest National Laboratory
Publications - 50
Citations - 2233
Ryan McClure is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 15, co-authored 38 publications receiving 1274 citations. Previous affiliations of Ryan McClure include Boston University.
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Journal ArticleDOI
Microbiome definition re-visited: old concepts and new challenges
Gabriele Berg,Daria Rybakova,Doreen Fischer,Tomislav Cernava,Marie Christine Champomier Vergès,Trevor C. Charles,Xiaoyulong Chen,Luca Simone Cocolin,Kellye Eversole,Gema Herrero Corral,Maria Kazou,Linda L. Kinkel,Lene Lange,Nelson Lima,Alexander Loy,James Macklin,Emmanuelle Maguin,Tim H. Mauchline,Ryan McClure,Birgit Mitter,M.J. Ryan,Inga Sarand,Hauke Smidt,Bettina Schelkle,Hugo Roume,G. Seghal Kiran,Joseph Selvin,Rafael Soares Correa de Souza,Leo van Overbeek,Brajesh K. Singh,Michael Wagner,Aaron M. Walsh,Angela Sessitsch,Michael Schloter +33 more
TL;DR: A definition of microbiome is proposed based on the compact, clear, and comprehensive description of the term provided by Whipps et al. in 1988, amended with a set of novel recommendations considering the latest technological developments and research findings.
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Computational analysis of bacterial RNA-Seq data
Ryan McClure,Divya Balasubramanian,Yan Sun,Maksym Bobrovskyy,Paul Sumby,Caroline A. Genco,Carin K. Vanderpool,Brian Tjaden +7 more
TL;DR: The results suggest that Rockhopper can be used for efficient and accurate analysis of bacterial RNA-seq data, and that it can aid with elucidation of bacterial transcriptomes.
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TLR-Dependent Human Mucosal Epithelial Cell Responses to Microbial Pathogens.
Ryan McClure,Paola Massari +1 more
TL;DR: The mechanisms by which TLR signaling is regulated in mucosal epithelial cells include differential expression and levels of TLRs, their cellular localization and positioning within the tissue in a fashion that favors responses to pathogens while dampening responses to commensals and maintaining tissue homeostasis in physiologic conditions.
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Soil Microbiomes Under Climate Change and Implications for Carbon Cycling
Dan Naylor,Natalie C. Sadler,Arunima Bhattacharjee,Emily B. Graham,Emily B. Graham,Christopher R. Anderton,Ryan McClure,Mary S. Lipton,Kirsten S. Hofmockel,Kirsten S. Hofmockel,Janet K. Jansson +10 more
TL;DR: In this article, the authors focus on the roles that the soil microbiome plays in biogeochemical cycles and support of plant growth, focusing primarily on the role of soil microorganisms (soil microbiomes).
Journal ArticleDOI
The Gonococcal Transcriptome during Infection of the Lower Genital Tract in Women.
Ryan McClure,Kathleen Nudel,Paola Massari,Brian Tjaden,Xiao-Hong Su,Peter A. Rice,Caroline A. Genco +6 more
TL;DR: It is demonstrated that a large portion of the gonococcal genome is expressed and regulated during mucosal infection including genes involved in regulatory functions and iron scavenging.