S
Samir Jana
Researcher at University of Calcutta
Publications - 14
Citations - 430
Samir Jana is an academic researcher from University of Calcutta. The author has contributed to research in topics: Metastasis & Epithelial–mesenchymal transition. The author has an hindex of 9, co-authored 13 publications receiving 323 citations.
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Journal ArticleDOI
CXCL13–CXCR5 co-expression regulates epithelial to mesenchymal transition of breast cancer cells during lymph node metastasis
Subir Biswas,Suman Sengupta,Sougata Roy Chowdhury,Samir Jana,Gunjan Mandal,Palash Kumar Mandal,Nipun Saha,Vivek Malhotra,Arnab Gupta,Dmitry V. Kuprash,Arindam Bhattacharyya +10 more
TL;DR: The EMT-inducing potential of CXCL13 is shown as well as the prognostic value of C XCL13–CXCR5 co-expression in primary BC is demonstrated, suggesting that CxCL13-CX CR5–RANKL–Src axis may present a therapeutic target in LNM positive BC patients.
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An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin.
Samuel M. Meier,Dominique Kreutz,Lilli Winter,Matthias H. M. Klose,Klaudia Cseh,Tamara Weiss,Andrea Bileck,Beatrix Alte,Johanna C. Mader,Samir Jana,Annesha Chatterjee,Arindam Bhattacharyya,Michaela Hejl,Michael A. Jakupec,Petra Heffeter,Walter Berger,Christian G. Hartinger,Bernhard K. Keppler,Gerhard Wiche,Christopher Gerner +19 more
TL;DR: Plectin targeting shows potential as a strategy to inhibit tumor invasiveness as shown in cultured tumor spheroids while oral administration of plecstatin-1 to mice reduces tumor growth more efficiently in the invasive B16 melanoma than in the CT26 colon tumor model.
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miR-216b suppresses breast cancer growth and metastasis by targeting SDCBP.
TL;DR: The study identifies miR-216b as a regulator of SDCBP expression in breast cancer which can potentially be targeted for developing newer therapies for the effective treatment of this killer disease.
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Transforming growth factor beta orchestrates PD-L1 enrichment in tumor-derived exosomes and mediates CD8 T-cell dysfunction regulating early phosphorylation of TCR signalome in breast cancer
Soumya Chatterjee,Annesha Chatterjee,Samir Jana,Subhasis Dey,Himansu Roy,Mrinal Kanti Das,Jahirul Alam,Anindya Adhikary,Abhisek Chowdhury,Anupam Biswas,Debasis Manna,Arindam Bhattacharyya +11 more
TL;DR: TGF-β is established as a promoter of exosomal PD-L1 and a mechanism that tumor cells follow to promote CD8 T cell dysfunction is unveiled, which synergistically attenuates tumor burden.
Journal ArticleDOI
MicroRNA-222 reprogrammed cancer-associated fibroblasts enhance growth and metastasis of breast cancer
Annesha Chatterjee,Samir Jana,Soumya Chatterjee,Laura M. Wastall,Gunjan Mandal,Nelofar Nargis,Himansu Roy,Thomas A. Hughes,Arindam Bhattacharyya +8 more
TL;DR: MiR-222/LBR have key roles in controlling pro-progression influences of CAFs in BC and this pathway may present therapeutic opportunities to inhibit CAF-induced cancer progression.