Sandra Mersakova

TL;DR: In this article, the authors discuss the results of most recent studies evaluating the impact of flavonoids on HIF-1 accompanied by the regulation of critical enzymes contributing to the Warburg phenotype.

TL;DR: The aim of this review is to summarize and compare the most common molecular methods for detection of methylated promoter regions in biomarkers occurring in cervical carcinoma and show the importance of connections of HR-HPV testing with methylation analysis in patients with cervical intraepithelial neoplasia.

TL;DR: This research presents a novel and scalable approach to personalized medicine that aims to provide real-time information about the immune system’s response to chemotherapy.

TL;DR: Investigating the methylation pattern of the CDH1 promoter suggested that methylation at these sites may be an important event in the transcriptional regulation of E-cadherin, and in patients harboring these methylated cytosines, this event may facilitate HPV-driven carcinogenesis.

TL;DR: Investigating the methylation levels in intronic sequences of the two tumor suppressor genes cell adhesion molecule 1 (CADM1) and T-lymphocyte maturation associated protein (MAL) using cytological samples and to identify potential biomarkers involved in CIN by pyrosequencing confirmed that there were statistically significant differences between themethylation levels of individual CpGs and significantly higher median methylation in patients positive for HPV16/18.