S
Sarah Curran
Researcher at King's College London
Publications - 78
Citations - 7948
Sarah Curran is an academic researcher from King's College London. The author has contributed to research in topics: Autism & Attention deficit hyperactivity disorder. The author has an hindex of 36, co-authored 77 publications receiving 7179 citations. Previous affiliations of Sarah Curran include Sussex Partnership NHS Foundation Trust & Brighton and Sussex Medical School.
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Journal ArticleDOI
No association between low- and high-activity catecholamine-methyl-transferase (COMT) and attention deficit hyperactivity disorder (ADHD) in a sample of Turkish children.
TL;DR: It is concluded that altered regulation of catecholamines due to this polymorphism does not have a significant main effect on the risk for ADHD in this population, however, it remains feasible that more minor effects or interacting effects with other genes or environment exist.
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Approaches to gene mapping in complex disorders and their application in child psychiatry and psychology
Philip Asherson,Sarah Curran +1 more
TL;DR: The most robust finding in ADHD is the association of a variable number tandem repeat polymorphism in exon 3 of the DRD4 gene and other replicated associations with ADHD are outlined in the text.
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The utility of patient specific induced pluripotent stem cells for the modelling of Autistic Spectrum Disorders
Graham Cocks,Sarah Curran,Priya Gami,Dafe Uwanogho,Aaron R. Jeffries,Annie Kathuria,Walter Lucchesi,Victoria Wood,Rosemary Dixon,Caroline Mackie Ogilvie,Thomas Steckler,Jack Price +11 more
TL;DR: A methodological evaluation of the current state of the iPS technology with reference to the author's own work in generating patient-specific iPSCs for the study of autistic spectrum disorder (ASD).
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Hypescheme: an operational criteria checklist and minimum data set for molecular genetic studies of attention deficit and hyperactivity disorders.
TL;DR: The development of Hypescheme is described, which is an operational criteria checklist for ADHD, oppositional defiant disorder (ODD), and conduct disorder (CD), and is proposed as a minimum dataset for those engaged in molecular genetic studies of ADHD.
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Polymorphisms in the dopamine D4 receptor gene and attention-deficit hyperactivity disorder.
TL;DR: None of the markers genotyped across the dopamine D4 receptor gene are individually associated with ADHD, although there is evidence to suggest that a haplotype of markers in the 5′ promoter region of the gene may confer susceptibility.