S
Sébastien Blugeon
Researcher at Agro ParisTech
Publications - 12
Citations - 4073
Sébastien Blugeon is an academic researcher from Agro ParisTech. The author has contributed to research in topics: Lactococcus lactis & Colitis. The author has an hindex of 9, co-authored 12 publications receiving 3471 citations. Previous affiliations of Sébastien Blugeon include Institut national de la recherche agronomique.
Papers
More filters
Journal ArticleDOI
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
Harry Sokol,Bénédicte Pigneur,Laurie Watterlot,Omar Lakhdari,Luis G. Bermúdez-Humarán,Jean-Jacques Gratadoux,Sébastien Blugeon,Chantal Bridonneau,Jean-Pierre Furet,Gérard Corthier,Corinne Grangette,Nadia Vasquez,Philippe Pochart,Germain Trugnan,Ginette Thomas,Hervé M. Blottière,Joël Doré,Philippe Marteau,Philippe Seksik,Philippe Langella +19 more
TL;DR: The results suggest that counterbalancing dysbiosis using F. prausnitzii as a probiotic is a promising strategy in CD treatment and exhibits anti-inflammatory effects on cellular and TNBS colitis models, partly due to secreted metabolites able to block NF-κB activation and IL-8 production.
Journal ArticleDOI
Intragastric administration of a superoxide dismutase-producing recombinant Lactobacillus casei BL23 strain attenuates DSS colitis in mice.
Laurie Watterlot,Tatiana Rochat,Harry Sokol,Claire Cherbuy,Ismael Bouloufa,François Lefèvre,Jean-Jacques Gratadoux,Edith Honvo-Hueto,Stefan Chilmonczyk,Sébastien Blugeon,Gérard Corthier,Philippe Langella,Luis G. Bermúdez-Humarán +12 more
TL;DR: Results suggest that Lb.
Journal ArticleDOI
Identification of One Novel Candidate Probiotic Lactobacillus plantarum Strain Active against Influenza Virus Infection in Mice by a Large-Scale Screening
Noura Kechaou,Florian Chain,Jean-Jacques Gratadoux,Sébastien Blugeon,Nicolas Bertho,Christophe Chevalier,Ronan Le Goffic,Stéphanie Courau,Pascal Molimard,Jean-Marc Chatel,Philippe Langella,Luis G. Bermúdez-Humarán +11 more
TL;DR: A novel candidate probiotic strain, L. plantarum CNRZ1997, was identified, active against influenza virus infection in mice, and led to a significant improvement in mouse health by reducing weight loss, alleviating clinical symptoms, and inhibiting significantly virus proliferation in lungs.
Journal ArticleDOI
Anti‐inflammatory properties of dairy lactobacilli
Clarissa Santos Rocha,Clarissa Santos Rocha,Clarissa Santos Rocha,Omar Lakhdari,Omar Lakhdari,Hervé M. Blottière,Hervé M. Blottière,Sébastien Blugeon,Sébastien Blugeon,Harry Sokol,Luis G. Bermúdez-Humarán,Luis G. Bermúdez-Humarán,Vasco Azevedo,Anderson Miyoshi,Joël Doré,Joël Doré,Philippe Langella,Philippe Langella,Emmanuelle Maguin,Emmanuelle Maguin,Maarten van de Guchte,Maarten van de Guchte +21 more
TL;DR: The results of this study show that dairy lactobacilli that often are part of a regular diet can modulate innate immune responses, and may thus affect health more than generally thought.
Journal ArticleDOI
Production of Fibronectin Binding Protein A at the surface of Lactococcus lactis increases plasmid transfer in vitro and in vivo.
Daniela Santos Pontes,Daniela Santos Pontes,Silvia Innocentin,Silvia Innocentin,Silvina del Carmen,Juliana Franco Almeida,Juliana Franco Almeida,Jean Guy LeBlanc,Alejandra de Moreno de LeBlanc,Sébastien Blugeon,Sébastien Blugeon,Claire Cherbuy,Claire Cherbuy,François Lefèvre,Vasco Azevedo,Anderson Miyoshi,Philippe Langella,Philippe Langella,Jean-Marc Chatel,Jean-Marc Chatel +19 more
TL;DR: The potential of LL-FnBPA+ as an in vivo DNA vaccine delivery vehicle was characterized and the good potential of invasive recombinant lactic acid bacteria as DNA delivery vector in vivo was confirmed.