S
Sébastien Boutet
Researcher at SLAC National Accelerator Laboratory
Publications - 221
Citations - 19765
Sébastien Boutet is an academic researcher from SLAC National Accelerator Laboratory. The author has contributed to research in topics: Femtosecond & Laser. The author has an hindex of 61, co-authored 207 publications receiving 17171 citations. Previous affiliations of Sébastien Boutet include Lawrence Livermore National Laboratory & Fermilab.
Papers
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Journal ArticleDOI
Towards phasing using high X-ray intensity.
Lorenzo Galli,Sang-Kil Son,Thomas R. M. Barends,Thomas A. White,Anton Barty,Sabine Botha,Sébastien Boutet,Carl Caleman,R. Bruce Doak,Max H. Nanao,Karol Nass,Robert L. Shoeman,Nicusor Timneanu,Robin Santra,Ilme Schlichting,Henry N. Chapman +15 more
TL;DR: Analysis of serial femtosecond crystallography data collected at the Linac Coherent Light Source using two distinct photon fluxes shows different degrees of ionization of Gd atoms bound to a lysozyme protein, due to electronic damage processes.
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Focal Spot and Wavefront Sensing of an X-Ray Free Electron laser using Ronchi shearing interferometry.
Bob Nagler,Andrew Aquila,Sébastien Boutet,Eric Galtier,Akel Hashim,Mark S. Hunter,Mengning Liang,Anne Sakdinawat,Christian G. Schroer,Andreas Schropp,Matthew Seaberg,Frank Seiboth,Tim Brandt van Driel,Zhou Xing,Yanwei Liu,Hae Ja Lee +15 more
TL;DR: This paper for the first time characterise this nanofocused beam in both phase and intensity using a Ronchi Shearing Interferometric technique, which is fast, in-situ, uses a straightforward optimization algoritm, and is insensitive to spatial jitter.
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Coherent diffractive imaging of microtubules using an X-ray laser.
Gisela Brändén,Greger Hammarin,Rajiv Harimoorthy,Alexander Johansson,David Arnlund,Erik Malmerberg,Anton Barty,Stefan Tångefjord,Peter Berntsen,Daniel P. DePonte,Carolin Seuring,Thomas A. White,Francesco Stellato,Richard Bean,Kenneth R. Beyerlein,Leonard M. G. Chavas,H. Fleckenstein,Cornelius Gati,Umesh Ghoshdastider,Lars Gumprecht,Dominik Oberthür,David Popp,M. Marvin Seibert,Thomas Tilp,Marc Messerschmidt,Garth J. Williams,N. Duane Loh,Henry N. Chapman,Peter H. Zwart,Mengning Liang,Mengning Liang,Sébastien Boutet,Robert Robinson,Robert Robinson,Robert Robinson,Richard Neutze +35 more
TL;DR: N nanoscale x-ray imaging of microtubules with helical symmetry is performed, by using imaging sorting and reconstruction techniques, to illustrate the potential of single-molecule X-ray Imaging of biological assembles withhelical symmetry at room temperature.
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Structural studies of P-type ATPase–ligand complexes using an X-ray free-electron laser
Maike Bublitz,Karol Nass,Nikolaj D. Drachmann,Anders J. Markvardsen,Matthias J. Gutmann,Thomas R. M. Barends,Daniel Mattle,Robert L. Shoeman,R. Bruce Doak,Sébastien Boutet,Marc Messerschmidt,M. Marvin Seibert,Garth J. Williams,Lutz Foucar,Linda Reinhard,Oleg Sitsel,Jonas Lindholt Gregersen,Johannes D. Clausen,Thomas Boesen,Kamil Gotfryd,Kaituo Wang,Claus Olesen,Jesper V. Møller,Poul Nissen,Ilme Schlichting +24 more
TL;DR: The structure determination of P-type ATPase–ligand complexes from microcrystals by serial femtosecond crystallography using a free-electron laser and the feasibility of the method for ligand screening is demonstrated and SFX data quality metrics are discussed.
Journal ArticleDOI
3D printed droplet generation devices for serial femtosecond crystallography enabled by surface coating.
Austin Echelmeier,Daihyun Kim,Jorvani Cruz Villarreal,Jesse Coe,Sebastian Quintana,Gerrit Brehm,Ana Egatz-Gomez,Reza Nazari,Raymond G. Sierra,Jason E. Koglin,Alexander Batyuk,Mark S. Hunter,Sébastien Boutet,Nadia A. Zatsepin,Richard A. Kirian,Thomas D. Grant,Petra Fromme,Alexandra Ros +17 more
TL;DR: The full compatibility of the new injection method with very fragile membrane protein crystals is demonstrated and successful droplet generation of crystal-laden aqueous droplets intersected by an oil phase correlates with increased crystal hit rates.