Sébastien Boutet

TL;DR: In this paper, a single-shot wavefront sensor for x-ray free electron laser (FEL) beams using single grating Talbot interferometry has been developed, which can be used to systematically study the wavefront from the FEL output, beam transport optics, and endstation focusing optics.

TL;DR: The observation and analysis of the gain curve of amplified Kα x-ray emission from solutions of Mn(II) and Mn(VII) complexes using an x-rays free electron laser to create the 1s core-hole population inversion is reported.

TL;DR: It is shown that the lifetime of a nanostructured sample can be extended to several picoseconds by a tamper layer to dampen and quench the sample explosion, making <1 nm resolution imaging feasible.

TL;DR: A femtosecond time-resolved X-ray pump/X-ray probe SFX experiment on protein nanocrystals observes distinct structural changes in the disulfide bridges and peptide backbone of proteins; complementing theoretical approaches allow them to further characterize the details of the X- Ray induced ionization and local structural dynamics.

TL;DR: The rhodopsin-arrestin crystal structure solved with SFX represents the first near-atomic resolution structure of a GPCR-Arrestin complex, provides structural insights into understanding of arrestin-mediated GPCRs signaling, and demonstrates the great potential of this SFX-XFEL technology for accelerating crystal structure determination of challenging proteins and protein complexes.