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Shangbang Gao
Researcher at Huazhong University of Science and Technology
Publications - 55
Citations - 1334
Shangbang Gao is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Medicine & Neurotransmission. The author has an hindex of 16, co-authored 44 publications receiving 988 citations. Previous affiliations of Shangbang Gao include Lunenfeld-Tanenbaum Research Institute & University of Toronto.
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Journal ArticleDOI
An Imbalancing Act: Gap Junctions Reduce the Backward Motor Circuit Activity to Bias C. elegans for Forward Locomotion
Taizo Kawano,Michelle D. Po,Michelle D. Po,Shangbang Gao,George Y. Leung,William S. Ryu,Mei Zhen,Mei Zhen +7 more
TL;DR: It is demonstrated that imbalanced motoneuron activity underlies directional movement and establishes gap junctions as critical modulators of the properties and outputs of neural circuits.
Journal ArticleDOI
Action potentials drive body wall muscle contractions in Caenorhabditis elegans
Shangbang Gao,Mei Zhen +1 more
TL;DR: This study shows that C. elegans body wall muscles fire all-or-none, calcium-dependent action potentials that are driven by the L-type voltage-gated calcium and Kv1 voltage-dependent potassium channels, and reveals a mode of motor control in which muscle cells integrate graded inputs of the nervous system and respond with all- or-none electrical signals.
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Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning
Zhaoqiang Wang,Zhaoqiang Wang,Lanxin Zhu,Hao Zhang,Guo Li,Chengqiang Yi,Yi Li,Yicong Yang,Yichen Ding,Mei Zhen,Shangbang Gao,Tzung K. Hsiai,Peng Fei +12 more
TL;DR: In this article, a view-channel-depth (VCD) neural network was combined with light-field microscopy to mitigate artifacts, yielding artifact-free three-dimensional image sequences with uniform spatial resolution and high-video-rate reconstruction throughput.
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MADD-4/Punctin and Neurexin Organize C. elegans GABAergic Postsynapses through Neuroligin
Géraldine S. Maro,Shangbang Gao,Agnieszka Olechwier,Wesley Hung,Michael Liu,Engin Özkan,Mei Zhen,Kang Shen +7 more
TL;DR: It is proposed that presynaptic terminals induce postsynaptic receptor clustering through the action of both secreted ECM proteins and trans-synaptic adhesion complexes.
Journal ArticleDOI
Excitatory motor neurons are local oscillators for backward locomotion.
Shangbang Gao,Sihui Asuka Guan,Sihui Asuka Guan,Anthony D. Fouad,Jun Meng,Jun Meng,Taizo Kawano,Yung-Chi Huang,Yi Li,Salvador Alcaire,Salvador Alcaire,Wesley Hung,Yangning Lu,Yangning Lu,Yingchuan Billy Qi,Yishi Jin,Mark J. Alkema,Christopher Fang-Yen,Mei Zhen,Mei Zhen +19 more
TL;DR: Motor neurons themselves derive rhythms, which are dually regulated by the descending interneurons to control the reversal motor state, and exemplify compression: essential circuit properties are conserved but executed by fewer numbers and layers of neurons in a small locomotor network.