S
Sharmishtaa Seshamani
Researcher at Allen Institute for Brain Science
Publications - 41
Citations - 1158
Sharmishtaa Seshamani is an academic researcher from Allen Institute for Brain Science. The author has contributed to research in topics: Biology & Iterative reconstruction. The author has an hindex of 12, co-authored 36 publications receiving 777 citations. Previous affiliations of Sharmishtaa Seshamani include Johns Hopkins University & Washington University in St. Louis.
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Journal ArticleDOI
Label-free prediction of three-dimensional fluorescence images from transmitted-light microscopy.
TL;DR: A label-free method for predicting three-dimensional fluorescence directly from transmitted-light images is presented and it is demonstrated that it can be used to generate multi-structure, integrated images.
Posted ContentDOI
Label-free prediction of three-dimensional fluorescence images from transmitted light microscopy
TL;DR: A label-free method for predicting 3D fluorescence directly from transmitted light images is presented and it is demonstrated that it can be used to generate multi-structure, integrated images.
Journal ArticleDOI
A Unified Approach to Diffusion Direction Sensitive Slice Registration and 3-D DTI Reconstruction From Moving Fetal Brain Anatomy
Mads Fogtmann,Sharmishtaa Seshamani,Christopher D. Kroenke,Xi Cheng,Teresa Chapman,Jakob Wilm,François Rousseau,Colin Studholme +7 more
TL;DR: This paper presents an approach to 3-D diffusion tensor image (DTI) reconstruction from multi-slice diffusion weighted (DW) magnetic resonance imaging acquisitions of the moving fetal brain, showing improved rendition of cortical anatomy and extraction of white matter tracts.
Journal ArticleDOI
Single-cell transcriptomic evidence for dense intracortical neuropeptide networks
Stephen J. Smith,Uygar Sümbül,Lucas T. Graybuck,Forrest Collman,Sharmishtaa Seshamani,Rohan Gala,Olga Gliko,Leila Elabbady,Jeremy A. Miller,Trygve E. Bakken,Jean Rossier,Zizhen Yao,Ed Lein,Hongkui Zeng,Bosiljka Tasic,Michael Hawrylycz +15 more
TL;DR: Here, neuron-type-specific patterns of NP gene expression are used to offer specific, testable predictions regarding 37 peptidergic neuromodulatory networks that may play prominent roles in cortical homeostasis and plasticity.
Journal ArticleDOI
Assessment of Crohn’s Disease Lesions in Wireless Capsule Endoscopy Images
Rajesh Kumar,Qian Zhao,Sharmishtaa Seshamani,Gerard E. Mullin,Gregory D. Hager,Themistocles Dassopoulos +5 more
TL;DR: This work is the first study to systematically explore supervised classification for CD lesions, a classifier cascade to classify discrete lesions, as well as quantitative assessment of lesion severity, using a well-developed database of 47 studies.